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Updated: Jan 19, 2026

Author Spotlight: Development of a Minimally Invasive Large-Animal Model for Reliable and Reproducible Cardiovascular Research
Published on: October 20, 2023
Bland-White-Garland syndrome with aortic stenosis
Mahmoud Y Ibrahim Abuharb1, Xiao Ming Bian1, Jian He1
1Department of Cardiovascular Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Background:
While anatomical variations in the cardiac circulation are quite commonly encountered, isolated congenital coronary artery anomalies are rare. These conditions are only reported in 1% of patients who underwent coronary angiogram and 0.3% of patients at autopsy.
Case Presentation:
This is the case of a 65-year-old female who presented with a 20-day history of postexertion chest tightness and shortness of breath. Coronary computed tomography exam revealed an anomalous left coronary artery from the pulmonary artery. With surgical intervention, the patient fully recovered.
Conclusion:
Due to the low incidence of abnormal origin of coronary artery among adults, this condition is often misdiagnosed as coronary artery spasm, resulting in delayed management. Lack of timely surgical intervention may lead to a poor prognosis.
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