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Updated: Jan 19, 2026

Stereotactically-guided Ablation of the Rat Auditory Cortex, and Localization of the Lesion in the Brain

Stereotactically-guided Ablation of the Rat Auditory Cortex, and Localization of the Lesion in the Brain

Published on: October 11, 2017

Ablative brain surgery: an overview.

Andrea Franzini^1,2, Shayan Moosa¹, Domenico Servello³

¹Department of Neurological Surgery, University of Virginia Health System , Charlottesville , VA , USA.

International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group

|September 21, 2019

Summary

This summary is machine-generated.

Ablative brain therapies, including radiofrequency thermoablation and laser interstitial thermal therapy, are resurging for neurological disorders. Advances enable precise lesioning for conditions like epilepsy and tumors.

Keywords:

Cerebral ablation high-intensity focused ultrasound laser interstitial thermal therapy magnetic resonance-guided focused ultrasound radiofrequency thermal lesioning

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Area of Science:

Neurosurgery
Medical Physics
Neurology

Background:

Ablative therapies create therapeutic lesions in the brain for neurological disorders and tumors.
Technological advances have improved safety and led to a resurgence of these techniques.
Key methods include radiofrequency thermoablation, stereotactic radiosurgery, laser interstitial thermal therapy, and MR-guided focused ultrasound.

Purpose of the Study:

To review the physical principles of brain ablative therapies.
To describe their applications in treating neurological disorders.

Main Methods:

Literature review of neurosurgical applications of brain ablative therapies.

Main Results:

Ablative treatments are effective for movement disorders, psychiatric conditions, chronic pain, epilepsy, and brain tumors.
Novel techniques offer precise targeting and real-time monitoring of tissue damage.
Established methods like radiofrequency thermal ablation remain crucial.

Conclusions:

Ongoing research focuses on developing new ablative therapies for brain conditions.
Advanced techniques like MR-guided focused ultrasound and laser interstitial thermal therapy enhance precision.
Older techniques continue to play a vital role in managing diverse neurological disorders.