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Postoperative creatine kinase elevation following hip arthroscopy and associated risk factors
Hisahiro Tonotsuka1, Hajime Sugiyama1, Daisuke Tanaka1
1Department of Orthopaedic Surgery, Kanagawa Rehabilitation Hospital, 516 Nanasawa, Atsugi, Kanagawa, Japan; Department of Orthopaedic Surgery, The Jikei University School of Medicine, 3-19-18 Nishishinbashi Minato-ku, Tokyo, Japan.
Insights
Postoperative creatine kinase (CK) levels can elevate after hip arthroscopy. Monitor CK in young patients and those with prolonged traction to mitigate risks.
Area of Science:
- Orthopedic Surgery
- Biochemistry
- Patient Monitoring
Background:
- Hip arthroscopy is a common orthopedic procedure.
- Postoperative creatine kinase (CK) elevation is a potential concern following surgical interventions.
- Understanding CK dynamics and risk factors is crucial for patient management.
Purpose of the Study:
- To investigate postoperative creatine kinase (CK) levels after hip arthroscopy.
- To identify independent risk factors associated with CK elevation post-hip arthroscopy.
Main Methods:
- Retrospective review of 122 patients undergoing hip arthroscopy.
- Serial CK measurements: preoperative, postoperative days 1 & 3, and weeks 1 & 2.
- Univariate and multivariate analyses to identify risk factors for CK > 10x upper limit of normal (ULN).
Main Results:
- CK levels were significantly higher on postoperative days 1 and 3 compared to pre-surgery.
- 9.0% of patients (11/122) experienced CK > 10x ULN.
- Younger age and longer duration of traction were identified as independent risk factors for elevated CK.
Conclusions:
- Creatine kinase (CK) monitoring is recommended after hip arthroscopy.
- Particular attention should be paid to younger patients.
- Prolonged intraoperative traction duration is a significant risk factor for CK elevation.
Objective:
The aim of this study was to investigate postoperative CK and risk factors for CK elevation after hip arthroscopy.
Methods:
This retrospective study reviewed 122 patients (50 males, 72 females; mean age, 44.1 years) who underwent hip arthroscopy from September 2012 to March 2018. For all patients, CK was investigated preoperatively, on postoperative days 1 and 3, and at postoperative weeks 1 and 2. Univariate and multivariate analysis was performed for parameters including sex, age, body mass index, preoperative glomerular filtration rate, diagnosis, duration of surgery, and duration of traction to determine the risk factors for CK > 10 upper limit of normal (CK > 10 ULN; 1900 IU/L for males and 1500 IU/L for females) after surgery.
Results:
Mean CK was 104.7 ± 68.7 IU/L preoperatively and 839.2 ± 2214.0, 523.9 ± 1449.4, 186.0 ± 690.7, and 122.0 ± 307.1 IU/L on postoperative days 1 and 3 and at postoperative weeks 1 and 2, respectively. CK was significantly higher on postoperative days 1 and 3 than before surgery. In total, 11 patients (9.0%), including 8 males (16.0%) and 3 females (4.2%), had CK > 10 ULN. Younger age and longer duration of traction are independent risk factors for CK > 10 ULN.
Conclusion:
After hip arthroscopy, CK levels should be monitored, especially in young patients and cases of prolonged duration of traction during surgery.
Level Of Evidence:
Level IV, therapeutic study.
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