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Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS

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Published on: July 11, 2016

Myroides spp. cellulitis and bacteremia: A case report.

Amy Meyer¹, Harry Dang², William Roland³

¹School of Medicine, University of Missouri, Columbia, MO 65212, United States.

|September 21, 2019

Summary

This case report details a rare instance of Myroides lower extremity cellulitis and bacteremia. Early identification is crucial due to the pathogen

Keywords:

Bacteremia Cellulitis Myroides

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Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA

Published on: February 9, 2011

Area of Science:

Medical Microbiology
Infectious Diseases
Clinical Case Reports

Background:

Myroides spp., previously classified as Flavobacterium spp., are rare, opportunistic gram-negative pathogens.
These bacteria are infrequently isolated, with limited documented cases of human infection since the 1920s.
Myroides infections are often associated with multidrug resistance, complicating treatment.

Observation:

A case of lower extremity cellulitis and bacteremia caused by Myroides spp. is presented.
This represents the 16th reported case of cutaneous infection attributed to Myroides spp.
The patient had pre-existing lower extremity wounds, type 2 diabetes, and chronic inhaled steroid use, suggesting potential immunosuppression.

Findings:

The patient's infection was likely acquired through exposure of wounds to soil and water or a dog lick.
Myroides spp. exhibit characteristic multidrug resistance, often rendering standard cellulitis empiric treatments ineffective.
The potential for pan-resistance in Myroides spp. poses a significant risk of fatal outcomes.

Implications:

Clinicians must maintain a high index of suspicion for Myroides spp. in patients with unusual or resistant infections.
Awareness of this rare pathogen is essential for appropriate diagnostic workup and antimicrobial stewardship.
Further research into Myroides spp. pathogenesis and treatment strategies is warranted.