Related Experiment Video
Updated: Jan 19, 2026

07:36
Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
11.8K
Communication in children born very preterm: a prospective cohort study
Katherine Sanchez1,2, Jessica O Boyce1,2, Cristina Mei1
1Murdoch Children's Research Institute, Parkville, Victoria, Australia.
Developmental Medicine and Child Neurology
|September 21, 2019
Summary
Children born preterm, especially before 30 weeks gestation, show poorer language development. Male sex, social risk, and neurodevelopmental diagnosis impact language outcomes in preterm infants.
Area of Science:
- Developmental Pediatrics
- Speech-Language Pathology
- Neonatology
Background:
- Premature birth (<30 weeks gestation) can impact child development.
- Language, speech, and voice are crucial developmental domains.
- Identifying predictors of developmental outcomes is essential for early intervention.
Purpose of the Study:
- To compare language, speech, and voice in children born preterm versus at term.
- To identify predictors of language, speech, and voice outcomes in preterm infants.
Main Methods:
- Prospective study of 300 infants (149 preterm, 151 term-born).
- Assessment at 3 years using standardized language, speech, and voice evaluations.
- Analysis of predictors including gestational age, birthweight, sex, chronic lung disease, social risk, and neurodevelopmental diagnosis.
Main Results:
- Children born preterm exhibited poorer language skills compared to term-born children.
- Speech and voice outcomes were comparable between preterm and term-born groups.
- Chronic lung disease predicted voice quality; male sex, high social risk, and neurodevelopmental diagnosis predicted poorer language outcomes.
Conclusions:
- Preterm infants, particularly those born before 30 weeks gestation, face challenges in language development.
- Neurodevelopmental disabilities and high social risk are significant predictors of poorer language outcomes in preterm children.
- Targeted language enrichment strategies are recommended for preterm infants with identified risk factors.

