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Updated: Jan 19, 2026

The Establishment of a Murine Mandibular Molar Extraction Socket Healing Model
Published on: January 13, 2023
Complication in third molar extractions
V Candotto1, L Oberti2, F Gabrione2
1Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.
Abstract:
Mandibular third molars (MM3s) are responsible for pericoronitis, primary and/or secondary crowding of the dentition, odontogenic tumors and cysts, periodontal defects associated with the posterior part of mandibular second molars. Tooth extraction is indicated for prophylactic and therapeutic purpose in patients with problems caused by impacted teeth. Common postoperative complications associated with third molar extraction are alveolitis (0.5e32.5%), infection (0.9e4.2%), postoperative bleeding (0.2e1.5%), transient dysfunction of the inferior alveolar nerve (0.6e5.5%), and permanent dysfunction of the inferior alveolar nerve (0.1e0.9%). A literature review reveals number of individual case reports of accidental displacement to various anatomical locations, namely, the infratemporal fossa, pterygomandibular space, lateral pharyngeal space, submandibular space, and sublingual space.
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