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Two Cases of Borrelia miyamotoi Meningitis, Sweden, 2018
Emerging Infectious Diseases
|September 21, 2019
Abstract:
We report 2 human cases of Borrelia miyamotoi disease diagnosed in Sweden, including 1 case of meningitis in an apparently immunocompetent patient. The diagnoses were confirmed by 3 different independent PCR assays and DNA sequencing from cerebrospinal fluid, supplemented by serologic analyses.
Insights
Two human cases of Borrelia miyamotoi disease were diagnosed in Sweden. One case involved meningitis in an immunocompetent individual, confirmed by PCR and sequencing.
Area of Science:
- Infectious Diseases
- Neurology
- Microbiology
Background:
- Borrelia miyamotoi is an emerging tick-borne pathogen.
- Human infections with Borrelia miyamotoi are rare and can cause serious illness.
Observation:
- Two human cases of Borrelia miyamotoi disease were diagnosed in Sweden.
- One patient presented with meningitis, despite being immunocompetent.
Findings:
- Diagnoses were confirmed using three independent PCR assays and DNA sequencing of cerebrospinal fluid.
- Serologic analyses supplemented the diagnostic findings.
Implications:
- This report highlights the potential for Borrelia miyamotoi to cause severe neurological disease, even in immunocompetent individuals.
- Increased awareness and diagnostic capabilities for Borrelia miyamotoi infection are crucial in endemic regions.

