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Beware of the dog - Capnocytophga Canimorsus septic shock: a case report
L Sabia1, D Marchesini, G Pignataro
1Department of Emergency Medicine, Fondazione Policlinico A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy. mcandelli@gmail.com.
Abstract:
Capnocytophaga canimorsus is a Gram-negative rods frequently isolated as commensal in the saliva of pets that can be transmitted to humans. We report a case of septic shock caused by this pathogen. A 78-year-old man affected by diabetes and hypertension was admitted for fever in our Emergency Department. He reported fever (37.7°C) with normal values of blood pressure, heart rate and saturation of oxygen. Laboratory studies showed increased values of procalcitonin and normal white-cell level. Blood cultures were collected and an empirical antibiotic therapy was started. He reported six days earlier a bite of a dog at the right hand. During the following days the patient presented a deterioration of clinical conditions with fever, asthenia and comparison of petechial lesions. C. canimorsus was isolated from blood cultures. He was treated with fluids and appropriate antibiotic therapy with a full recovery. Dog wounds are frequent minor injuries with an underestimated worldwide incidence because only few patients develop complications. C. canimorsus could be an emerging cause of sepsis, also in immunocompetent patients. The current understanding of risk factors for C. canimorsus associated sepsis and a prompt approach to anamnesis and treatment of early stage injuries, could have a considerable medical outcome.
Insights
Capnocytophaga canimorsus, a bacterium from pet saliva, can cause severe sepsis, even in healthy individuals. Prompt treatment of dog bites is crucial to prevent serious complications like septic shock.
Area of Science:
- Infectious Diseases
- Bacteriology
- Critical Care Medicine
Background:
- Capnocytophaga canimorsus is a Gram-negative bacterium commonly found in canine and feline saliva.
- Transmission to humans can occur through bites or scratches, potentially leading to severe infections.
- While often asymptomatic, C. canimorsus can cause serious systemic illness, including sepsis and septic shock.
Observation:
- A 78-year-old male with diabetes and hypertension presented with fever and elevated procalcitonin levels.
- The patient reported a dog bite on his hand six days prior to admission.
- Clinical deterioration included persistent fever, asthenia, and petechial lesions.
Findings:
- Blood cultures confirmed the presence of Capnocytophaga canimorsus.
- The patient received supportive care with fluids and appropriate antibiotics.
- Successful treatment resulted in a full recovery from septic shock.
Implications:
- Capnocytophaga canimorsus represents an emerging cause of sepsis, even in immunocompetent individuals.
- Recognizing the risk factors and prompt management of animal-related injuries are vital.
- Early diagnosis and treatment can significantly improve patient outcomes and reduce mortality.
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