Prostate MRI technical parameters standardization: A systematic review on adherence to PI-RADSv2 acquisition protocol

Renato Cuocolo1, Arnaldo Stanzione1, Andrea Ponsiglione1

  • 1Department of Advanced Biomedical Sciences, University of Naples "Federico II", Via Pansini 5, Naples, Italy.

Abstract

Insights

Adherence to Prostate Imaging-Reporting and Data System (PI-RADSv2) technical standards for prostate MRI is inconsistent among studies. Greater guideline dissemination and potential streamlining are needed for better standardization and clinical applicability.

Area of Science:

  • Radiology
  • Medical Imaging

Background:

  • The Prostate Imaging-Reporting and Data System (PI-RADSv2) aims to standardize prostate MRI acquisition, interpretation, and reporting.
  • Recent concerns question adherence to PI-RADSv2 acquisition protocols in clinical practice.

Purpose of the Study:

  • To systematically review and assess adherence to PI-RADSv2 minimum technical specifications in published prostate MRI studies.
  • To identify factors limiting the widespread adoption of PI-RADSv2 acquisition protocols.

Main Methods:

  • A systematic search of medical literature databases was conducted for original studies published after January 2016 on prostate MRI.
  • Acquisition protocols and patient enrollment data were extracted and analyzed.
  • Technical parameters were evaluated against PI-RADSv2 minimal technical requirements.

Main Results:

  • Out of 150 included studies, only 5% reported all PI-RADSv2 technical parameters, and none fully met all specifications.
  • Overall adherence to PI-RADSv2 acquisition parameters was observed in 19% of studies.
  • Lowest adherence rates were found for T2-weighted in-plane resolution (12%), DWI field of view (40%), ADC map low b-value (27%), and DCE-MRI temporal resolution (43%).
  • Only 59% of studies followed recommendations for diffusion-weighted imaging high b-value.

Conclusions:

  • Adherence to PI-RADSv2 minimum technical standards is highly variable within the scientific literature.
  • Enhanced dissemination of PI-RADSv2 guidelines is crucial for achieving protocol standardization.
  • Some PI-RADSv2 requirements may need revision to improve clinical applicability and facilitate wider adoption.