Alcohol-Related Hospital Encounters Trigger Thrombotic and Hemorrhagic Vascular Events

Caroline Gentile1, Laura Stein1, Mandip S Dhamoon1

  • 1Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, New York.

Insights

Recent alcohol-related encounters are linked to vascular events like stroke, but not intracerebral hemorrhage. Alcohol use also increases the risk of hospital readmission after these events.

Area of Science:

  • Neurology
  • Public Health
  • Epidemiology

Background:

  • Alcohol consumption is a significant public health concern.
  • Vascular events represent a major cause of morbidity and mortality.

Purpose of the Study:

  • To investigate the association between alcohol-related emergency department visits and hospitalizations and specific vascular events.
  • To examine the impact of alcohol-related encounters on hospital readmission rates following vascular events.

Main Methods:

  • Utilized New York State Inpatient and Emergency Department Databases (2006-2013).
  • Employed case cross-over analysis with conditional logistic regression to assess associations.
  • Used multivariate logistic regression to evaluate the impact on 30-day readmissions.

Main Results:

  • Alcohol encounters were associated with increased odds of acute ischemic stroke and subarachnoid hemorrhage.
  • No significant association was found between alcohol encounters and intracerebral hemorrhage (ICH).
  • Alcohol-related encounters within six months prior to index vascular events increased the likelihood of 30-day readmission.

Conclusions:

  • Recent alcohol-related encounters are associated with the occurrence of specific vascular events, excluding ICH.
  • Alcohol use is linked to poorer outcomes, including higher readmission rates, after index vascular admissions.
Abstract

Related Concept Videos

Disorders of Hemostasis01:24

Disorders of Hemostasis

Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
2.0K
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
205
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
281
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
397
Extrinsic and Intrinsic Pathways of Hemostasis01:20

Extrinsic and Intrinsic Pathways of Hemostasis

Blood clotting or coagulation involves extrinsic and intrinsic pathways, which ultimately merge into the common pathway, forming a fibrin clot.
The Extrinsic Pathway
The extrinsic pathway of coagulation is typically initiated by tissue damage that exposes blood to tissue factor (TF), a protein released by the damaged tissue cells outside the blood vessels—this interaction with TF triggers biochemical reactions involving specific clotting factors. The key player here is Factor VII, which...
12.2K
Esophageal Varices-I: Introduction01:24

Esophageal Varices-I: Introduction

Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
1.2K