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Alcohol-Related Hospital Encounters Trigger Thrombotic and Hemorrhagic Vascular Events
Caroline Gentile1, Laura Stein1, Mandip S Dhamoon1
1Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, New York.
Insights
Recent alcohol-related encounters are linked to vascular events like stroke, but not intracerebral hemorrhage. Alcohol use also increases the risk of hospital readmission after these events.
Area of Science:
- Neurology
- Public Health
- Epidemiology
Background:
- Alcohol consumption is a significant public health concern.
- Vascular events represent a major cause of morbidity and mortality.
Purpose of the Study:
- To investigate the association between alcohol-related emergency department visits and hospitalizations and specific vascular events.
- To examine the impact of alcohol-related encounters on hospital readmission rates following vascular events.
Main Methods:
- Utilized New York State Inpatient and Emergency Department Databases (2006-2013).
- Employed case cross-over analysis with conditional logistic regression to assess associations.
- Used multivariate logistic regression to evaluate the impact on 30-day readmissions.
Main Results:
- Alcohol encounters were associated with increased odds of acute ischemic stroke and subarachnoid hemorrhage.
- No significant association was found between alcohol encounters and intracerebral hemorrhage (ICH).
- Alcohol-related encounters within six months prior to index vascular events increased the likelihood of 30-day readmission.
Conclusions:
- Recent alcohol-related encounters are associated with the occurrence of specific vascular events, excluding ICH.
- Alcohol use is linked to poorer outcomes, including higher readmission rates, after index vascular admissions.
Background And Purpose:
We investigated the associations between alcohol-related emergency department visits and hospitalizations and vascular events including acute ischemic stroke, intracerebral hemorrhage (ICH), and subarachnoid hemorrhage.
Methods:
The New York State Inpatient and Emergency Department Databases were examined (2006-2013). Validated International Classification of Diseases 9th edition definitions identified index vascular hospitalizations and alcohol abuse encounters. We used case cross-over analysis with conditional logistic regression to estimate odds ratios (OR) for the association between alcohol-related encounters during 6 case periods (7, 14, 30, 60, 90, and 120 days before index event) compared to control periods (1 year before). Multivariate logistic regression was used to examine the association between an alcohol-related encounter within 6 months before index admission and 30-day readmission after discharge.
Results:
An alcohol encounter before index admission was associated with acute ischemic stroke (OR = 1.765 within 60 days, 1.418 within 90 days, and 1.287 within 120 days) and subarachnoid hemorrhage (OR = 2.375 within 90 days), but not ICH. Alcohol-related encounters within 6 months before index vascular events increased the likelihood of 30-day readmission after index admission.
Conclusion:
We found that a recent alcohol-related counter was associated with occurrence of vascular events, but not ICH, as well as worse outcomes after index admission.
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