Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Imaging Studies for Cardiovascular System V: CT

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...

Acute Coronary Syndrome III: Diagnostic Studies

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...

Imaging Studies for Cardiovascular System IV: CMRI

Imaging Studies for Cardiovascular System IV: CMRI

Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...

Assessment of Diffusion and Perfusion

Assessment of Diffusion and Perfusion

Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Analysis of Pericoronary Adipose Tissue Attenuation in Patients with Type 2 Diabetes Mellitus on Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers: A Propensity-Score-Matched Observational Study.

Biomedicines·2026

Same author

Fractional flow reserve in coronary computed tomography angiography: An expert consensus document of the society of cardiovascular computed tomography (SCCT) and the society for cardiovascular angiography and interventions (SCAI). Endorsed by the American college of cardiology (ACC).

Journal of cardiovascular computed tomography·2026

Same author

Per-vessel myocardial blood flow improvement after coronary artery bypass graft surgery quantified by CT myocardial perfusion imaging.

Journal of cardiovascular computed tomography·2026

Same author

Correction to: 2025 ACC/AHA/ASE/ASNC/SCCT/SCMR Advanced Training Statement on Advanced Cardiovascular Imaging: A Report of the ACC Competency Management Committee.

Circulation. Cardiovascular imaging·2026

Same author

Quantitative Coronary CT Angiography and the Power of Numbers.

JACC. Cardiovascular imaging·2026

Same author

The association of risk factors on coronary computed tomography angiography derived atherosclerotic plaque volume - Lessons from the ADVANCE registry.

Atherosclerosis·2026

Search research articles

Related Experiment Video

Updated: Jan 19, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

Dynamic CT myocardial perfusion imaging.

Koen Nieman¹, Sujana Balla¹

¹Stanford University School of Medicine and Cardiovascular Institute, Stanford University School of Medicine, Room H2157, 300 Pasteur Drive, Stanford, CA, 94304, USA.

Journal of Cardiovascular Computed Tomography

|September 22, 2019

Summary

This summary is machine-generated.

Dynamic myocardial perfusion CT (MPI_CT) quantifies blood flow in the heart muscle. This review details MPI_CT methods, performance, and its role in assessing coronary artery disease severity.

Keywords:

Computed tomography Coronary artery disease Myocardial blood flow Myocardial perfusion imaging

More Related Videos

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

Published on: December 16, 2022

Author Spotlight: Improved Localization and Monitoring of Coronary Flow Reserve Using Modified PLAX View in Mice

Author Spotlight: Improved Localization and Monitoring of Coronary Flow Reserve Using Modified PLAX View in Mice

Published on: August 25, 2023

Related Experiment Videos

Last Updated: Jan 19, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

Published on: December 16, 2022

Author Spotlight: Improved Localization and Monitoring of Coronary Flow Reserve Using Modified PLAX View in Mice

Author Spotlight: Improved Localization and Monitoring of Coronary Flow Reserve Using Modified PLAX View in Mice

Published on: August 25, 2023

Area of Science:

Cardiovascular Imaging
Radiology
Medical Physics

Background:

Cardiac CT provides methods to assess coronary artery obstruction severity.
Myocardial perfusion CT (MPI_CT) uses serial imaging to measure contrast inflow and calculate absolute myocardial perfusion.

Purpose of the Study:

To review the acquisition protocol, post-processing, and quantitative parameter calculation for MPI_CT.
To evaluate the diagnostic performance and incremental value of MPI_CT compared to other methods.

Main Methods:

Description of MPI_CT acquisition protocols.
Explanation of image post-processing and quantitative parameter calculation.
Analysis of diagnostic performance data.

Main Results:

MPI_CT enables quantitative assessment of myocardial perfusion.
The review discusses the diagnostic performance and potential benefits of MPI_CT.

Conclusions:

Further technical advancements and standardized diagnostic thresholds are needed for widespread clinical adoption of MPI_CT.
MPI_CT shows potential for differentiating significant coronary artery disease.