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Related Experiment Video

Updated: Jan 19, 2026

Use of In Vivo Imaging to Screen for Morphogenesis Phenotypes in Candida albicans Mutant Strains During Active Infection in a Mammalian Host
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Minimum Information in In Vivo Research.

Patrizia Voehringer1, Janet R Nicholson2

  • 1Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany.

Handbook of Experimental Pharmacology
|September 22, 2019
PubMed
Summary

Ensuring data quality in biomedical research requires precise reporting of in vivo study details. This chapter outlines essential information for transparent scientific publications to improve reproducibility and accelerate drug development.

Keywords:
BehaviorData qualityIn vivoPublicationReportingReproducibilityStandards

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Area of Science:

  • Biomedical Research
  • Scientific Rigor

Background:

  • Data quality, reproducibility, and reliability are critical in scientific research.
  • Robust data underpins future studies, knowledge gain, and drug development.
  • Precise and transparent data reporting is essential for scientific integrity.

Purpose of the Study:

  • To describe the minimum information needed for reporting in vivo research.
  • To focus on essential information for scientific publications.
  • To differentiate between internal records and published data.

Main Methods:

  • Literature review on reporting factors for in vivo studies.
  • Development of a table comparing internal protocols and publication requirements.
  • Inclusion of examples from behavioral, anesthesia/analgesia, and ex vivo studies.

Main Results:

  • Identification of key factors for minimum information reporting in scientific publications.
  • Distinction between data recorded internally versus data reported externally.
  • Illustrative examples from diverse in vivo and ex vivo experimental contexts.

Conclusions:

  • Establishing clear reporting standards enhances data quality and reproducibility.
  • Transparent reporting accelerates scientific discovery and therapeutic innovation.
  • Guidelines provided will aid researchers in meeting publication requirements.