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Related Concept Videos

Lateralization01:28

Lateralization

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Brain lateralization refers to the division of mental processes and functions between the two hemispheres of the brain, a phenomenon that optimizes neural efficiency and underpins complex abilities in humans. This specialization allows each hemisphere to perform tasks where it has a comparative advantage, facilitating more refined cognitive capabilities across different domains.
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Cognitive Development During Adulthood

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Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
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Related Experiment Video

Updated: Jan 19, 2026

Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice
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Improved Accuracy on Lateralized Spatial Judgments in Healthy Aging.

John B Williamson1,2,3, Aidan Murphy1,2, Damon G Lamb1,2,3

  • 1Brain Rehabilitation Research Center (151A), Malcom Randall VAMC, 1601 SW Archer Road, Gainesville, FL 32608, USA.

Journal of the International Neuropsychological Society : JINS
|September 24, 2019
PubMed
Summary
This summary is machine-generated.

Older adults show improved accuracy in spatial tasks, suggesting reduced hemispheric asymmetry. This challenges the right hemi-aging theory and supports the HAROLD model of aging brain networks.

Keywords:
Character line bisectionLine bisectionLine trisectionPseudoneglectSpatial attention

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Area of Science:

  • Cognitive Neuroscience
  • Human Aging
  • Spatial Cognition

Background:

  • Healthy young adults exhibit pseudoneglect, a leftward spatial bias.
  • This bias often diminishes with age, with two hypotheses: right hemi-aging or Hemispheric Asymmetry Reduction in Older Adults (HAROLD).

Purpose of the Study:

  • To investigate age-related changes in spatial attention and bias.
  • To differentiate between the right hemi-aging and HAROLD hypotheses.

Main Methods:

  • Seventy healthy, right-handed participants (33 younger, 37 older) performed line bisection and trisection tasks.
  • Tasks involved solid and character-letter lines, with left and right trisections.

Main Results:

  • Both age groups showed leftward bias on solid line bisections/left trisections and rightward bias on character line bisections/right trisections.
  • Older adults demonstrated significantly greater accuracy across all spatial tasks compared to younger adults.

Conclusions:

  • Increased accuracy in older adults suggests reduced hemispheric asymmetry in spatial attention networks.
  • Findings support the HAROLD model over the right hemi-aging hypothesis for explaining age-related changes in spatial bias.