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Post-SSRI sexual dysfunction & other enduring sexual dysfunctions.

David Healy1

  • 1Bangor University, Psychiatry, Bangor, Gwynedd, UK.

Epidemiology and Psychiatric Sciences
|September 24, 2019
PubMed
Summary
This summary is machine-generated.

Selective serotonin reuptake inhibitor (SSRI) antidepressants can cause persistent sexual side effects. Researchers are using epidemiological methods to understand this post-SSRI sexual dysfunction syndrome and find potential treatments.

Keywords:
Adverse effectsantidepressantsdrug side effects othersexual dysfunction

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Area of Science:

  • Pharmacology
  • Psychiatry
  • Epidemiology

Background:

  • Reports of enduring sexual difficulties linked to SSRI antidepressants date back to 1991.
  • A formal syndrome, post-SSRI sexual dysfunction (PSSD), was described in 2006.
  • The clinical, research, and regulatory implications of PSSD are significant.

Purpose of the Study:

  • To formally report and define post-SSRI sexual dysfunction (PSSD).
  • To highlight the considerable clinical, research, and regulatory implications of PSSD.
  • To emphasize the role of epidemiological methods in characterizing PSSD and identifying treatments.

Main Methods:

  • Utilizing epidemiological research methods.
  • Analyzing reported cases and clinical data.
  • Mapping the scope and characteristics of the syndrome.

Main Results:

  • Formal recognition of post-SSRI sexual dysfunction syndrome in 2006.
  • Identification of enduring sexual difficulties following SSRI treatment.
  • Established the need for further research into PSSD.

Conclusions:

  • PSSD is a recognized condition with significant implications.
  • Epidemiological approaches are crucial for understanding PSSD.
  • Further research is needed to pinpoint effective treatments for PSSD.