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Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction

Sifan Chen1, Ayana Henderson2, Michael C Petriello3

  • 1Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China; Division of Endocrinology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.

Cell Metabolism
|September 24, 2019
PubMed
Abstract

Keywords:
EIF2AK3FoxO1PERKdiabetesendoplasmic reticulum stressinsulin signalingmetabolomicstrimethylamine N-oxide

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