Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving01:29

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving

292
Mechanistic models play a crucial role in algorithms for numerical problem-solving, particularly in nonlinear mixed effects modeling (NMEM). These models aim to minimize specific objective functions by evaluating various parameter estimates, leading to the development of systematic algorithms. In some cases, linearization techniques approximate the model using linear equations.
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
292
Gaussian Elimination: Problem Solving01:30

Gaussian Elimination: Problem Solving

162
Systems of linear equations in several variables are pivotal in modeling complex scenarios involving multiple unknowns and constraints. Such systems are widely used in various fields to represent relationships where several conditions must be simultaneously satisfied. Each variable in the system corresponds to an unknown quantity, while each equation imposes a linear constraint, leading to a structured approach for analyzing and solving real-world problems.A system of three equations with three...
162
One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation01:24

One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation

1.1K
This lesson introduces two critical methods in pharmacokinetics, the Wagner-Nelson and Loo-Riegelman methods, used for estimating the absorption rate constant (ka) for drugs administered via non-intravenous routes. The Wagner-Nelson method relates ka to the plasma concentration derived from the slope of a semilog percent unabsorbed time plot. However, it is limited to drugs with one-compartment kinetics and can be impacted by factors like gastrointestinal motility or enzymatic degradation.
On...
1.1K
Model Approaches for Pharmacokinetic Data: Distributed Parameter Models01:06

Model Approaches for Pharmacokinetic Data: Distributed Parameter Models

243
Pharmacokinetic models are mathematical constructs that represent and predict the time course of drug concentrations in the body, providing meaningful pharmacokinetic parameters. These models are categorized into compartment, physiological, and distributed parameter models.
The distributed parameter models are specifically designed to account for variations and differences in some drug classes. This model is particularly useful for assessing regional concentrations of anticancer or...
243
Distributions to Estimate Population Parameter01:26

Distributions to Estimate Population Parameter

5.0K
The accurate values of population parameters such as population proportion, population mean, and population standard deviation (or variance) are usually unknown. These are fixed values that can only be estimated from the data collected from the samples. The estimates of each of these parameters are sample proportion, the sample mean, and sample standard deviation (or variance). To obtain the values of these sample statistics, data are required that have particular distribution and central...
5.0K
Cluster Sampling Method01:20

Cluster Sampling Method

14.1K
Appropriate sampling methods ensure that samples are drawn without bias and accurately represent the population. Because measuring the entire population in a study is not practical, researchers use samples to represent the population of interest.
To choose a cluster sample, divide the population into clusters (groups) and then randomly select some of the clusters. All the members from these clusters are in the cluster sample. For example, if you randomly sample four departments from your...
14.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High-dimensional multivariate geostatistics: A Bayesian matrix-normal approach.

Environmetrics·2026
Same author

Mechanisms and scales in modeling forest responses to changing disturbance regimes.

The New phytologist·2026
Same author

Systematic estimates of global causes of neonatal and under 5 mortality in 2000-24: secondary data analysis using bayesian multinomial logistic regression.

BMJ (Clinical research ed.)·2026
Same author

Leveraging Artificial Intelligence in Allergy, Asthma, and Immunology With Environmental Exposures.

Allergy·2026
Same author

Bayesian Inference for Spatially-Temporally Misaligned Data Using Predictive Stacking.

Environmetrics·2026
Same author

Bayesian Inference for Spatial-Temporal Non-Gaussian Data Using Predictive Stacking.

Bayesian analysis·2026
Same journal

Probabilistic Joint and Individual Variation Explained (ProJIVE) for Data Integration.

Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America·2026
Same journal

fastkqr: A Fast Algorithm for Kernel Quantile Regression.

Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America·2026
Same journal

Empirical Bayes Covariance Decomposition, and a Solution to the Multiple Tuning Problem in Sparse PCA.

Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America·2026
Same journal

Joint Registration and Conformal Prediction for Partially Observed Functional Data.

Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America·2026
Same journal

Efficient Decision Trees for Tensor Regressions.

Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America·2026
Same journal

Distributed Nonparametric Regression with Heterogeneity Through Prediction-Based Aggregation.

Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America·2026
See all related articles

Related Experiment Video

Updated: Jan 19, 2026

Author Spotlight: UAV Remote Sensing for Efficient Invasive Plant Biomass Estimation
08:47

Author Spotlight: UAV Remote Sensing for Efficient Invasive Plant Biomass Estimation

Published on: February 9, 2024

2.1K

Efficient algorithms for Bayesian Nearest Neighbor Gaussian Processes.

Andrew O Finley1, Abhirup Datta2, Bruce C Cook3

  • 1Michigan State University.

Journal of Computational and Graphical Statistics : a Joint Publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America
|September 24, 2019
PubMed
Summary
This summary is machine-generated.

This study introduces improved Nearest Neighbor Gaussian Process (NNGP) models for faster, more reliable forest canopy mapping. The enhanced models provide the first statistically robust forest canopy map for Alaska's Tanana Inventory Unit.

More Related Videos

A Psychophysics Paradigm for the Collection and Analysis of Similarity Judgments
08:12

A Psychophysics Paradigm for the Collection and Analysis of Similarity Judgments

Published on: March 1, 2022

2.9K

Related Experiment Videos

Last Updated: Jan 19, 2026

Author Spotlight: UAV Remote Sensing for Efficient Invasive Plant Biomass Estimation
08:47

Author Spotlight: UAV Remote Sensing for Efficient Invasive Plant Biomass Estimation

Published on: February 9, 2024

2.1K
A Psychophysics Paradigm for the Collection and Analysis of Similarity Judgments
08:12

A Psychophysics Paradigm for the Collection and Analysis of Similarity Judgments

Published on: March 1, 2022

2.9K

Area of Science:

  • Environmental science
  • Computer science
  • Statistical modeling

Background:

  • Nearest Neighbor Gaussian Process (NNGP) models offer a framework for spatial data analysis.
  • Existing NNGP models face challenges in computational efficiency and reproducibility.
  • Hierarchical NNGP models have been proposed to address these limitations.

Purpose of the Study:

  • To develop and evaluate alternate formulations of hierarchical Nearest Neighbor Gaussian Process (NNGP) models.
  • To improve computational performance, including convergence speed and CPU memory management.
  • To enhance the robustness and reproducibility of Bayesian inference for spatial modeling.

Main Methods:

  • Development of novel algorithms for NNGP models.
  • Integration of high-performance numerical linear algebra libraries.
  • Assessment of computational and inferential benefits using simulated and real-world remote sensing data (LiDAR).

Main Results:

  • Demonstrated improvements in CPU memory management and computational speed.
  • Validated the effectiveness of alternate NNGP specifications through simulations.
  • Generated the first statistically robust forest canopy map for the Tanana Inventory Unit (TIU) using LiDAR data.

Conclusions:

  • Alternate NNGP formulations offer significant computational and inferential advantages.
  • The developed methods enable more efficient and reliable spatial data analysis.
  • The resulting forest canopy map provides valuable ecological insights for the TIU.