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Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
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The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
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Herpes Simplex Virus Type 2 Radiculomyelitis Disguised as Conversion Disorder.

Lisa B E Shields1, Mohammad S Alsorogi1

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Herpes simplex virus type 2 (HSV-2) can cause radiculomyelitis, a serious spinal cord condition. Early detection via cerebrospinal fluid PCR and treatment with acyclovir is crucial for preventing severe neurological damage.

Keywords:
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Area of Science:

  • Neurology
  • Infectious Diseases
  • Virology

Background:

  • Herpes simplex virus type 2 (HSV-2) is a common cause of genital herpes.
  • HSV-2 is linked to neurological complications, including neonatal encephalitis, meningitis, and radiculomyelitis.
  • Radiculomyelitis presents with symptoms such as pain, weakness, and sensory disturbances.

Observation:

  • A patient with a psychiatric history presented with lower extremity pain and weakness.
  • Initial MRI scans were normal, leading to a suspected diagnosis of conversion disorder.
  • Cerebrospinal fluid (CSF) PCR detected HSV-2 and lymphocytic pleocytosis, confirming radiculomyelitis.

Findings:

  • The case highlights HSV-2 as a cause of radiculomyelitis, often misdiagnosed initially.
  • Prompt diagnosis via CSF PCR is essential for appropriate treatment.
  • Treatment with intravenous acyclovir followed by oral valacyclovir was initiated.

Implications:

  • Neurologists must consider HSV-2 in patients with radiculomyelitis, especially those with psychiatric comorbidities.
  • Early recognition and treatment of HSV-2 radiculomyelitis may prevent long-term neurological deficits.
  • This case underscores the importance of considering infectious etiologies in neurological presentations.