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Related Experiment Video

Updated: Jan 19, 2026

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography
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Macular choroidal thickness in Chinese preschool children: decrease with axial length but no evident change with age.

Xian-Gui He1,2,3, Jun-Jie Deng2,3, Yao Yin2

  • 1Department of Maternal and Child Health, School of Public Health, Key Laboratory of Public Health Safety, Ministry of Education, Fudan University, Shanghai 200032, China.

International Journal of Ophthalmology
|September 24, 2019
PubMed
Summary

Choroidal thickness (ChT) in Chinese preschoolers is stable with age but negatively associated with axial length. This finding aids understanding early refractive development and ocular health in children.

Keywords:
choroidal thicknessoptical coherence tomographypreschool childrenrefractive error

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Area of Science:

  • Ophthalmology
  • Pediatric Optometry
  • Retinal Imaging

Background:

  • Macular choroidal thickness (ChT) is a key indicator of ocular health.
  • Understanding ChT development in early childhood is crucial for monitoring refractive development.

Purpose of the Study:

  • To investigate the distribution of macular choroidal thickness (ChT) in Chinese preschoolers.
  • To analyze the association between ChT, age, and refractive status in this population.

Main Methods:

  • A cross-sectional study involving 550 healthy Chinese preschoolers aged 3-6 years.
  • Ocular examinations included visual acuity, axial length, refraction, and swept-source optical coherence tomography (SS-OCT) for macular ChT measurement.
  • ChT was analyzed across ETDRS grid sectors and correlated with age, gender, and refractive parameters.

Main Results:

  • Mean central ChT was 312±59 µm. Axial length increased with age, but ChT remained stable across age groups and genders.
  • No significant differences in ChT were found across different refractive groups, although a trend towards thinner choroids in myopic children was observed.
  • Longer axial length and lower weight were independently associated with thinner central ChT.

Conclusions:

  • Macular ChT is relatively stable in preschool children.
  • A negative association exists between ChT and axial length, suggesting its importance in early refractive development.
  • These findings provide insights into the ocular characteristics influencing refractive development in young children.