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Updated: Jan 19, 2026

Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins
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Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins

Published on: August 15, 2017

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The Genomics of Electroconvulsive Therapy International Consortium (GenECT-ic)

Bernhard T Baune1, Takahiro Soda2,

  • 1Department of Psychiatry, University of Münster, Münster D-48149, Germany; Department of Psychiatry, Melbourne Medical School and The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC, Australia.

The Lancet. Psychiatry
|September 24, 2019
PubMed
Abstract

No abstract available in PubMed .

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Electroconvulsive Therapy01:30

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Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
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