Imaging with SPADs and DMDs: Seeing through Diffraction-Photons
Related Experiment Video
Updated: Jan 19, 2026

Patterned Photostimulation with Digital Micromirror Devices to Investigate Dendritic Integration Across Branch Points
Published on: March 2, 2011
Abstract:
This paper addresses the problem of imaging in the presence of diffraction-photons. Diffraction-photons arise from the low contrast ratio of DMDs (∼1000:1), and very much degrade the quality of images captured by SPAD-based systems. Herein, a joint illumination-deconvolution scheme is designed to overcome diffraction-photons, enabling the acquisition of intensity and depth images. Additionally, a proof-of-concept experiment is conducted to demonstrate the viability of the designed scheme. It is shown that by co-designing the illumination and deconvolution phases of imaging, one can substantially overcome diffraction-photons.
Related Concept Videos
X-ray Crystallography
Diffraction
Diffraction is the change in the direction of travel experienced by an electromagnetic wave when it encounters a physical barrier whose dimensions are comparable to those of the wavelength of the light. X-rays are electromagnetic radiation with wavelengths about as long as the distance between neighboring...
Interference and Diffraction
X-ray Diffraction of Biological Samples
According to Bragg's law, when X-rays strike the sample positioned on a stage, the rays are scattered by the electron clouds around the sample atoms. The X-ray diffraction or scattering is caused by constructive interference of the X-ray waves that reflect off the internal...
Phase Contrast and Differential Interference Contrast Microscopy
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
Super-resolution Fluorescence Microscopy
Three-Dimensional Microscopy in Microbiology

