Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

3.2K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
3.2K
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

2.1K
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.1K
Bone Disorders01:29

Bone Disorders

5.1K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
5.1K
Urinary Tract Calculi III: Medical Management01:30

Urinary Tract Calculi III: Medical Management

197
The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
197

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Management of Infected Wounds: A Wound Healing Foundation Consensus Statement.

Advances in wound care·2026
Same author

Antibiotic-loaded bone substitutes in the surgical management of diabetic foot osteomyelitis: Current evidence and clinical perspectives.

Diabetes research and clinical practice·2026
Same author

Absence of evidence or evidence of absence? Interpreting bone biopsy-guided therapy in diabetic foot osteomyelitis.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same author

Comparative Effectiveness of Transmetatarsal First Ray Amputation and Hallux Amputation in a Diabetic Foot Ulcer Cohort.

Foot & ankle international·2026
Same author

Short Against Long Antibiotic Therapy for Infected Orthopaedic Sites-2nd Interim Analysis of the SALATIO Trials.

Journal of clinical medicine·2026
Same author

Pertussis Infection in Adults.

JAMA·2026

Related Experiment Video

Updated: Jan 19, 2026

Surgical Bone Implantation Technique for Rat Tibia Models of Diabetes and Osteoporosis
02:08

Surgical Bone Implantation Technique for Rat Tibia Models of Diabetes and Osteoporosis

Published on: July 5, 2024

1.4K

Diabetic calcaneal osteomyelitis.

Felix W A Waibel1, Ilker Uçkay2, Kati Sairanen3

  • 1Department of Orthopedic Surgery, Balgrist University Hospital, Zurich, Switzerland.

Le Infezioni in Medicina
|September 24, 2019
PubMed
Summary
This summary is machine-generated.

Diabetic foot infection (DFI) can present as uncommon calcaneal osteomyelitis (CO). This review highlights CO

More Related Videos

Treatment with Vancomycin Loaded Calcium Sulphate and Autogenous Bone in an Improved Rabbit Model of Bone Infection
09:09

Treatment with Vancomycin Loaded Calcium Sulphate and Autogenous Bone in an Improved Rabbit Model of Bone Infection

Published on: March 14, 2019

9.4K
Measuring Bone Remodeling and Recreating the Tumor-Bone Microenvironment Using Calvaria Co-culture and Histomorphometry
08:24

Measuring Bone Remodeling and Recreating the Tumor-Bone Microenvironment Using Calvaria Co-culture and Histomorphometry

Published on: March 14, 2020

7.3K

Related Experiment Videos

Last Updated: Jan 19, 2026

Surgical Bone Implantation Technique for Rat Tibia Models of Diabetes and Osteoporosis
02:08

Surgical Bone Implantation Technique for Rat Tibia Models of Diabetes and Osteoporosis

Published on: July 5, 2024

1.4K
Treatment with Vancomycin Loaded Calcium Sulphate and Autogenous Bone in an Improved Rabbit Model of Bone Infection
09:09

Treatment with Vancomycin Loaded Calcium Sulphate and Autogenous Bone in an Improved Rabbit Model of Bone Infection

Published on: March 14, 2019

9.4K
Measuring Bone Remodeling and Recreating the Tumor-Bone Microenvironment Using Calvaria Co-culture and Histomorphometry
08:24

Measuring Bone Remodeling and Recreating the Tumor-Bone Microenvironment Using Calvaria Co-culture and Histomorphometry

Published on: March 14, 2020

7.3K

Area of Science:

  • Diabetology
  • Infectious Diseases
  • Podiatry
  • Orthopedic Surgery

Background:

  • Diabetic foot infection (DFI) is a common complication, typically affecting the forefoot.
  • Calcaneal osteomyelitis (CO) is a rare but distinct form of DFI with unique characteristics.
  • DFI management necessitates a multidisciplinary approach, with CO often requiring specialized interventions.

Purpose of the Study:

  • To differentiate calcaneal osteomyelitis (CO) from other diabetic foot infections (DFI) affecting different anatomical sites.
  • To provide non-surgical clinicians with insights into the distinct epidemiology, clinical features, and management of CO.
  • To emphasize the importance of specialized surgical techniques and off-loading strategies in CO treatment.

Main Methods:

  • This study is a narrative review of existing literature.
  • Personal clinical experience with calcaneal osteomyelitis cases was incorporated.
  • The review focuses on comparing CO with non-calcaneal DFI.

Main Results:

  • Calcaneal osteomyelitis (CO) presents differently from forefoot DFI in terms of epidemiology and clinical presentation.
  • Patients with CO are more likely to require specialized surgical interventions and off-loading techniques compared to those with DFI in other locations.
  • Effective management of CO necessitates tailored approaches, often involving advanced surgical methods.

Conclusions:

  • Calcaneal osteomyelitis (CO) is an uncommon but significant manifestation of diabetic foot infection (DFI).
  • Understanding the unique aspects of CO is crucial for non-surgical clinicians to guide appropriate patient referral and management.
  • Specialized surgical approaches and off-loading are frequently essential for successful outcomes in CO.