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Updated: Aug 2, 2026

Manufacture and Drug Delivery Applications of Silk Nanoparticles
Published on: October 8, 2016
Optimization of a low pressure plasma process for fabrication of a Drug Delivery System (DDS) for cancer treatment
Alibi Baitukha1, Iman Al-Dybiat2, Azadeh Valinataj-Omran2
1Sorbonne Universités, UPMC Univ Paris 06, CNRS, Laboratoire Interfaces et Systèmes Electrochimiques, 4 place Jussieu, 75005 Paris, France.
Abstract:
A low pressure ICP plasma setup was utilized to deposit thin organic barrier coatings on various substrates to fabricate DDS with encapsulated Carboplatin as a drug and Methylene Blue as a drug model. Choice of the substrates and optimal plasma parameters were discussed for the fabrication of DDS with required characteristics. Prepared thin films were analysed by FTIR, SEM, and the barrier properties were studied by measuring drug concentration released into the medium by UV-VIS and ICP-MS techniques.
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