Pre-Exposure Prophylaxis (PrEP) Use is Associated With Health Risk Behaviors Among Moderate- and Heavy-Drinking MSM

Peter Luehring-Jones1, Tibor P Palfai1, Kelli D Tahaney1

  • 1Department of Psychological and Brain Sciences, Boston University, Boston, Massachusetts.

Insights

Pre-exposure prophylaxis (PrEP) use among moderate- to heavy-drinking men who have sex with men is linked to riskier sexual behaviors and increased illicit drug use, suggesting a need for targeted interventions.

Area of Science:

  • Public Health
  • Behavioral Science
  • Infectious Disease Prevention

Background:

  • Acute alcohol consumption increases condomless sex among men who have sex with men (MSM), raising HIV/STI risks.
  • Pre-exposure prophylaxis (PrEP) uptake is increasing in MSM, but concerns exist regarding associated health risk behaviors.
  • Understanding PrEP use in conjunction with alcohol consumption and other risk factors is crucial for targeted prevention.

Purpose of the Study:

  • To investigate differences in sexual behaviors and drug use between PrEP users and nonusers among moderate- and heavy-drinking MSM.
  • To identify specific risk factors associated with PrEP use in this population.

Main Methods:

  • A comparative study design was employed.
  • Data on sexual behaviors, drug use, and PrEP status were collected from a sample of moderate- and heavy-drinking MSM.
  • Statistical analyses were used to compare PrEP users and nonusers.

Main Results:

  • PrEP use was associated with higher rates of riskier sexual practices.
  • Weaker self-regulatory cognitions regarding condom use were observed in PrEP users.
  • PrEP users reported more frequent illicit drug use compared to nonusers.
  • These associations were found within a sample of moderate- and heavy-drinking MSM.

Conclusions:

  • Moderate- and heavy-drinking MSM who use PrEP may represent a unique risk group.
  • Targeted counseling and interventions are recommended to mitigate negative health consequences in this population.
  • Further research is needed to develop effective strategies for this specific demographic.

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