Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Antimicrobial Proteins01:23

Antimicrobial Proteins

13.0K
Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
13.0K
Chemical Agents for Microbial Control01:27

Chemical Agents for Microbial Control

764
Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
764
Biological Methods for Microbial Control01:28

Biological Methods for Microbial Control

792
Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...
792
Synthetic Biology02:55

Synthetic Biology

5.5K
Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
5.5K
Bacterial Phylum Actinobacteria01:30

Bacterial Phylum Actinobacteria

622
Coryneform bacteria are gram-positive, aerobic, nonmotile rods that exhibit irregular, club-shaped, or V-shaped arrangements. Their V-shape results from snapping division, where the inner cell wall layer forms the cross-wall, while the outer layer remains intact until it ruptures on one side, causing the daughter cells to bend away.The primary genera are Corynebacterium and Arthrobacter. Corynebacterium includes diverse species, ranging from saprophytes to pathogens like Corynebacterium...
622

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Trefoil polymers from a knotted synthon.

Nature chemistry·2026
Same author

Deciphering unusually large modulations in two related organic hydroxy channel structures.

Acta crystallographica Section B, Structural science, crystal engineering and materials·2026
Same author

Steric Control of Cooperative Anion Transport Mediated by β- and δ‑Hexachlorocyclohexane Multivalent Carriers.

JACS Au·2026
Same author

Selective Nitrate Transmembrane Transport Through Adaptive Weak C─H Bonding Cyanostilbene Water Channels.

Angewandte Chemie (International ed. in English)·2026
Same author

Photo-modulation of proton/water transmembrane transport through bis(imidazole-amide)-tetrafluoro-azobenzene switch.

Faraday discussions·2026
Same author

Membrane potential mediates the cellular response to mechanical pressure.

Cell·2025
Same journal

An integrated annotation strategy for the phytochemical characterization of Xie-Bai-San decoction based on UPLC-Q Exactive Orbitrap HRMS, multi-database screening, and feature-based molecular networking.

Frontiers in chemistry·2026
Same journal

Core-shell structured nanomaterials in dual-modal magnetic resonance imaging guided antitumor effect via combined treatment.

Frontiers in chemistry·2026
Same journal

Photo-responsive nanozymes: from photocatalytic mechanisms to precision therapy.

Frontiers in chemistry·2026
Same journal

From theoretical energy to practical utilization: interfacial stability, transport kinetics, and cell-level design in high-energy lithium-metal batteries.

Frontiers in chemistry·2026
Same journal

Zinc-vacancy defects in ZnO nanorods induced visible-light activity of photoelectrochemical glucose sensing: experimental and DFT+U analysis.

Frontiers in chemistry·2026
Same journal

Integrating multi-isotope calibration and infrared-assisted digestion for robust and sustainable multielemental determination in agroalimentary matrices by ICP-MS.

Frontiers in chemistry·2026
See all related articles

Related Experiment Video

Updated: Jan 19, 2026

Synthesis of Masarimycin, a Small Molecule Inhibitor of Gram-Positive Bacterial Growth
09:10

Synthesis of Masarimycin, a Small Molecule Inhibitor of Gram-Positive Bacterial Growth

Published on: January 7, 2022

2.7K

Artificial Gramicidins.

Zhanhu Sun1, Mihail Barboiu1

  • 1Institut Europeen des Membranes, Adaptive Supramolecular Nanosystems Group, University of Montpellier, ENSCM-CNRS, Montpellier, France.

Frontiers in Chemistry
|September 26, 2019
PubMed
Summary
This summary is machine-generated.

Researchers are developing simple artificial systems that mimic Gramicidin A (gA) channel functions. These primitive mimics aid in understanding ion and water transport, crucial for bio-interfaces and artificial pathways.

Keywords:
biomimeticgramicidin Ahydrophilichydrophobicion channels

More Related Videos

A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries
09:39

A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries

Published on: December 27, 2016

18.5K
Gramicidin-based Fluorescence Assay; for Determining Small Molecules Potential for Modifying Lipid Bilayer Properties
10:52

Gramicidin-based Fluorescence Assay; for Determining Small Molecules Potential for Modifying Lipid Bilayer Properties

Published on: October 13, 2010

13.3K

Related Experiment Videos

Last Updated: Jan 19, 2026

Synthesis of Masarimycin, a Small Molecule Inhibitor of Gram-Positive Bacterial Growth
09:10

Synthesis of Masarimycin, a Small Molecule Inhibitor of Gram-Positive Bacterial Growth

Published on: January 7, 2022

2.7K
A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries
09:39

A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries

Published on: December 27, 2016

18.5K
Gramicidin-based Fluorescence Assay; for Determining Small Molecules Potential for Modifying Lipid Bilayer Properties
10:52

Gramicidin-based Fluorescence Assay; for Determining Small Molecules Potential for Modifying Lipid Bilayer Properties

Published on: October 13, 2010

13.3K

Area of Science:

  • Supramolecular chemistry
  • Biomimetic systems
  • Ion channel research

Background:

  • Gramicidin A (gA) is a natural protein channel facilitating cation and water transport.
  • The orientation of water molecules within the gA pore influences ion translocation.
  • Understanding ion and water dynamics in gA is challenging due to structural complexity.

Purpose of the Study:

  • To review the development of simple artificial systems that mimic Gramicidin A functions.
  • To highlight the relevance of these primitive mimics for understanding molecular translocation.
  • To explore how confined water and ion dynamics in artificial systems inform biological processes.

Main Methods:

  • Review of published supramolecular systems acting as Gramicidin A mimics.
  • Analysis of atomic-level designs for artificial channel systems.
  • Discussion of experimental and theoretical approaches to study confined water and ions.

Main Results:

  • Several supramolecular systems have been developed as primitive Gramicidin A mimics.
  • These artificial systems offer simpler models for studying ion and water dynamics.
  • Directional ordering of confined water and ions in mimics shows similarities to natural gA.

Conclusions:

  • Artificial systems provide crucial insights into molecular-level translocation mechanisms.
  • The dipolar orientation of water in artificial channels influences dielectric properties.
  • These findings are relevant for understanding biological recognition and charge transport in artificial pathways.