Related Experiment Video
Updated: Jan 19, 2026
Dynamic Contrast Enhanced Magnetic Resonance Imaging of an Orthotopic Pancreatic Cancer Mouse Model
Published on: April 18, 2015
Dynamic contrast-enhanced MR imaging of rectal cancer using a golden-angle radial stack-of-stars VIBE sequence:
Yuming Li1, Chunchao Xia1, Wanlin Peng1
1Department of Radiology, West China Hospital of Sichuan University, No. 37 Guo Xue Xiang, Chengdu, 610041, Sichuan, People's Republic of China.
Purpose:
To compare conventional 3D volumetric-interpolated breath-hold examination (C-VIBE) sequence image quality to that of golden-angle radial stack-of stars acquisition scheme (R-VIBE) in rectal cancer patients.
Methods:
Seventy-eight patients had undergone pre-contrast C-VIBE, followed by DCE-MRI with R-VIBE and post-contrast C-VIBE in the visualization of rectal cancer. The first phase and the last phase of R-VIBE sequence were compared with pre-contrast and post-contrast C-VIBE sequences, respectively. Signal-to-noise ratios (SNRs) and contrast-to-noise ratios (CNRs) of rectal neoplasms, gluteus maximus, and subcutaneous fat were compared between the two different sequences. A further qualitative score system (graded 1-5) was used to evaluate the overall image. Quantitative and qualitative parameters from the two sequences were compared.
Results:
In all patients, R-VIBE achieved the same SNR and CNR ratings in pre- and post-contrast (all P > 0.05), with the exception of a higher SNR of fat in pre-contrast images (P = 0.037). In addition, there were no significant differences in scores of overall image quality, lesion conspicuity, and rectal wall boundary (all P > 0.05). There was an improved score in artifacts of post-contrast R-VIBE sequence (P = 0.005).
Conclusion:
R-VIBE sequence can provide comparable image quality and less motion artifacts to that of C-VIBE sequence and is feasible for imaging of rectal cancer.
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