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Updated: Jan 19, 2026

Isolation and Cannulation of Cerebral Parenchymal Arterioles
Published on: May 23, 2016
Cervical arterial dissection: clinical characteristics in a neurology service in São Paulo, Brazil
Danyelle Sadala Reges1, Marcela Mazzeo2, Rafael Rosalino2
1Irmandade da Santa Casa de Misericórdia de São Paulo, Faculdade de Ciências Médicas da Santa Casa de São Paulo, Departamento de Medicina, Disciplina de Neurologia, São Paulo SP, Brasil.
Insights
Cervical arterial dissection, a cause of stroke, is linked to hypertension and smoking. Anticoagulation may improve recanalization compared to antiplatelet therapy, with favorable outcomes for both treatments.
Area of Science:
- Neurology
- Vascular Medicine
- Cardiology
Background:
- Cervical arterial dissection (CAD) is an uncommon cause of ischemic stroke.
- It presents with significant clinical variability, prompting further investigation.
Purpose of the Study:
- To identify risk factors for CAD.
- To describe clinical characteristics and treatment outcomes.
- To explore prognosis and compare antiplatelet vs. anticoagulant therapies.
Main Methods:
- Retrospective observational study.
- Analysis of medical records from January 2010 to August 2015.
- Inclusion of 41 patients diagnosed with cervical arterial dissection.
Main Results:
- The average age of patients was 44.5 years; smoking was the most frequent risk factor.
- Hypertension, smoking, and dyslipidemia were common, while atherosclerosis was rare.
- 43% of patients achieved recanalization within six months, with higher rates in the anticoagulation group (p=0.04).
Conclusions:
- Hypertension, smoking, and dyslipidemia are prevalent in CAD patients.
- Treatment choice between anticoagulation and antiplatelet therapy remains individualized.
- Both treatment strategies yielded similar clinical outcomes, but anticoagulation showed improved recanalization rates.
Abstract:
Cervical arterial dissection accounts for only a small proportion of ischemic stroke but arouses scientific interest due to its wide clinical variability. OBJECTIVE This study aimed to evaluate its risk factors, outline its clinical characteristics, compare treatment with antiaggregation or anticoagulation, and explore the prognosis of patients with cervical arterial dissection. METHODS An observational, retrospective study using data from medical records on patients with cervical arterial dissection between January 2010 and August 2015. RESULTS The total number of patients was 41. The patients' ages ranged from 19 to 75 years, with an average of 44.5 years. The most common risk factor was smoking. Antiaggregation was used in the majority of patients (65.5%); 43% of all patients recanalized in six months, more frequently in patients who had received anticoagulation (p = 0.04). CONCLUSION The presence of atherosclerotic disease is considered rare in patients with cervical arterial dissection; however, our study found a high frequency of hypertension, smoking and dyslipidemia. The choice of antithrombotic remains controversial and will depend on the judgment of the medical professional; the clinical results with anticoagulation or antiaggregation were similar but there was more recanalization in the group treated with anticoagulation; its course was favorable in both situations. The recurrence of cervical arterial dissection and stroke is considered a rare event and its course is favorable.
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