Cervical arterial dissection: clinical characteristics in a neurology service in São Paulo, Brazil

Danyelle Sadala Reges1, Marcela Mazzeo2, Rafael Rosalino2

  • 1Irmandade da Santa Casa de Misericórdia de São Paulo, Faculdade de Ciências Médicas da Santa Casa de São Paulo, Departamento de Medicina, Disciplina de Neurologia, São Paulo SP, Brasil.

Insights

Cervical arterial dissection, a cause of stroke, is linked to hypertension and smoking. Anticoagulation may improve recanalization compared to antiplatelet therapy, with favorable outcomes for both treatments.

Area of Science:

  • Neurology
  • Vascular Medicine
  • Cardiology

Background:

  • Cervical arterial dissection (CAD) is an uncommon cause of ischemic stroke.
  • It presents with significant clinical variability, prompting further investigation.

Purpose of the Study:

  • To identify risk factors for CAD.
  • To describe clinical characteristics and treatment outcomes.
  • To explore prognosis and compare antiplatelet vs. anticoagulant therapies.

Main Methods:

  • Retrospective observational study.
  • Analysis of medical records from January 2010 to August 2015.
  • Inclusion of 41 patients diagnosed with cervical arterial dissection.

Main Results:

  • The average age of patients was 44.5 years; smoking was the most frequent risk factor.
  • Hypertension, smoking, and dyslipidemia were common, while atherosclerosis was rare.
  • 43% of patients achieved recanalization within six months, with higher rates in the anticoagulation group (p=0.04).

Conclusions:

  • Hypertension, smoking, and dyslipidemia are prevalent in CAD patients.
  • Treatment choice between anticoagulation and antiplatelet therapy remains individualized.
  • Both treatment strategies yielded similar clinical outcomes, but anticoagulation showed improved recanalization rates.

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