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Dialysis modality-related disparities in sudden cardiac death: hemodialysis versus peritoneal dialysis

Hee-Yeon Jung1, Hyungyun Choi2, Ji-Young Choi1

  • 1Department of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, Republic of Korea.

Kidney Research and Clinical Practice
|September 26, 2019
PubMed

Insights

Patients on hemodialysis (HD) face a higher risk of sudden cardiac death (SCD) compared to those on peritoneal dialysis (PD). Cardiac comorbidities contribute to this increased SCD risk in HD patients.

Area of Science:

  • Nephrology
  • Cardiology
  • Public Health

Background:

  • Dialysis is a risk factor for sudden cardiac death (SCD).
  • Risk stratification and preventive strategies for SCD are crucial for dialysis patients.
  • Dialysis modality influences SCD risk.

Purpose of the Study:

  • To compare the risk of SCD in patients undergoing hemodialysis (HD) versus peritoneal dialysis (PD).
  • To identify factors associated with SCD based on dialysis modality.

Main Methods:

  • Analysis of patients from the Korean Society of Nephrology registry (1985-2017).
  • Inclusion of patients on HD and PD.
  • Propensity score matching and multivariable analysis to assess SCD risk factors.

Main Results:

  • Hemodialysis (HD) was independently associated with a higher risk of SCD compared to peritoneal dialysis (PD).
  • Cardiac comorbidities like hypertension, coronary artery disease, and heart failure were significant risk factors for SCD in HD patients.
  • Diabetes was a significant risk factor for SCD regardless of dialysis modality.

Conclusions:

  • Korean patients on HD have a higher risk of SCD than those on PD.
  • Cardiac comorbidities are a key factor contributing to the increased SCD risk in HD patients.
  • Tailored preventive strategies for SCD may be necessary based on dialysis modality.
Abstract

Keywords:
Coronary artery diseaseHeart failureHemodialysisHypertensionPeritoneal dialysisSudden cardiac death

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