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Updated: Jan 19, 2026

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice
Published on: August 2, 2017
Effect of Closed-Loop Vibration Stimulation on Heart Rhythm during Naps
Sang Ho Choi1, Heenam Yoon2, Hyung Won Jin3
1Interdisciplinary Program in Bioengineering, Graduate School, Seoul National University, Seoul 03080, Korea. csh412@bmsil.snu.ac.kr.
Abstract:
Sleep plays a primary function for health and sustains physical and cognitive performance. Although various stimulation systems for enhancing sleep have been developed, they are difficult to use on a long-term basis. This paper proposes a novel stimulation system and confirms its feasibility for sleep. Specifically, in this study, a closed-loop vibration stimulation system that detects the heart rate (HR) and applies -n% stimulus beats per minute (BPM) computed on the basis of the previous 5 min of HR data was developed. Ten subjects participated in the evaluation experiment, in which they took a nap for approximately 90 min. The experiment comprised one baseline and three stimulation conditions. HR variability analysis showed that the normalized low frequency (LF) and LF/high frequency (HF) parameters significantly decreased compared to the baseline condition, while the normalized HF parameter significantly increased under the -3% stimulation condition. In addition, the HR density around the stimulus BPM significantly increased under the -3% stimulation condition. The results confirm that the proposed stimulation system could influence heart rhythm and stabilize the autonomic nervous system. This study thus provides a new stimulation approach to enhance the quality of sleep and has the potential for enhancing health levels through sleep manipulation.
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