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Updated: Jul 30, 2026

Quantitative Fundus Autofluorescence for the Evaluation of Retinal Diseases
Published on: March 11, 2016
Ultra-wide-field fundus imaging of acute retinal necrosis: clinical characteristics and visual significance
Boya Lei1, Min Zhou1,2,3, Zhujian Wang1
1Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China.
Objectives:
To investigate the clinical characteristics of acute retinal necrosis (ARN) with ultra-wide-field imaging (UWFI) and analyse their visual significance.
Methods:
Clinical and UWFI records of patients diagnosed with ARN at a single centre over 2 years were reviewed.
Results:
In 38 eyes of 35 patients, the clinical manifestations of ARN on UWFI included patchy (12 eyes) or fan-shaped necrotic lesions (26 eyes), retinal arterial obliteration (38 eyes), vitritis (38 eyes), retinal venous haemorrhage (19 eyes), and vitreous haemorrhage (6 eyes). Retinal detachment was associated with the number of retinal quadrants involved (β = 2.145, P = 0.005). LogMAR BCVA at last follow-up was associated with logMAR BCVA at presentation (β = 0.473, P = 0.004) and retinal detachment (β = 0.367, P = 0.020).
Conclusion:
UWFI is useful for detecting retinal lesions in ARN, especially peripheral lesions or through opaque media, and provides valuable information concerning visual prognosis.

