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Updated: Jan 19, 2026

Measuring the Subjective Value of Risky and Ambiguous Options using Experimental Economics and Functional MRI Methods
Published on: September 19, 2012
Exploring the effect of risk and benefit information provision on vaccination decision-making
Mehrnaz Mostafapour1, Samantha B Meyer1, Abigail Scholer2
1University of Waterloo, School of Public Health and Health Systems, Canada.
Abstract:
In the era in which people are bombarded with misinformation about vaccination, research regarding the degree to which various types of risk or benefit information affect perceptions of vaccines and intentions to vaccinate is critical. The present research utilizes a robust methodology to quantify the extent to which risk and benefit information affects vaccination intentions. Our work demonstrates an inverse relationship between the perceived risks and benefits of a vaccine. By providing information about either risks or benefits of avaccine, our findings suggest that we can change one's perception of both the risks and benefits of thevaccine. Considering that the main cognitive barriers to vaccination are related to concerns about efficacy and safety, our results suggest thatvaccinemessages can be framed to address the audience's main concerns, whether it be about the low efficacy of thevaccineor its safety, knowing that both frames would carry similar outcomes.
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