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Updated: Jan 19, 2026

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
Published on: May 6, 2010
Visualising three-dimensional genome organisation in two dimensions
Elizabeth Ing-Simmons1, Juan M Vaquerizas1
1Max Planck Institute for Molecular Biomedicine, Roentgenstrasse 20, DE-48149 Muenster, Germany liz.ing-simmons@mpi-muenster.mpg.de jmv@mpi-muenster.mpg.de.
Abstract:
The three-dimensional organisation of the genome plays a crucial role in developmental gene regulation. In recent years, techniques to investigate this organisation have become more accessible to labs worldwide due to improvements in protocols and decreases in the cost of high-throughput sequencing. However, the resulting datasets are complex and can be challenging to analyse and interpret. Here, we provide a guide to visualisation approaches that can aid the interpretation of such datasets and the communication of biological results.
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