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Primary angiosarcoma of the breast: a case report
Mohamed Mouhoub1, Achraf Miry1, Anass Haloui1
1Department of Pathology, Mohamed VI University Hospital, Faculty of Medicine and Pharmacy of Oujda, Morocco.
The Pan African Medical Journal
|September 28, 2019
Summary
Primary breast angiosarcoma, a rare cancer, was diagnosed in an 18-year-old woman. This case highlights diagnostic challenges and treatment considerations for this aggressive vascular tumor.
Area of Science:
- Oncology
- Pathology
Background:
- Primary breast angiosarcoma is exceptionally rare, posing diagnostic and prognostic challenges.
- Mastectomy is the established treatment, but the roles of radiotherapy and chemotherapy remain unclear.
Observation:
- An 18-year-old woman presented with infectious symptoms and a rapidly growing breast mass.
- Initial treatment for infection led to symptom regression, but the mass persisted.
- Core needle biopsy revealed malignant vascular proliferation.
Findings:
- Histopathology confirmed angiosarcoma grade I, with atypical cells expressing CD34 and CD31.
- The patient underwent mastectomy and is currently undergoing chemotherapy.
Implications:
- This case underscores the importance of considering rare malignancies in breast pathology.
- Further research is needed to establish optimal adjuvant therapies for breast angiosarcoma.

