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The pathogens and curative effects analysis of perianal abscess of infants under 3 months
1Department of General Surgery, The First Affiliated Hospital of Lishui University, Lishui, China.
Insights
Klebsiella pneumoniae is the main cause of perianal abscess in infants under three months. Treatment involves simple incision and antibiotics, with a lower fistula complication rate compared to adults.
Area of Science:
- Pediatrics
- Infectious Diseases
- Microbiology
Background:
- Perianal abscesses in infants under three months require specific treatment guidelines.
- Understanding causative pathogens and their antibiotic susceptibility is crucial for effective management.
Purpose of the Study:
- To analyze the pathogens responsible for perianal abscesses in infants under three months.
- To evaluate the effectiveness of abscess incision and identify optimal antibiotic strategies.
Main Methods:
- Retrospective analysis of 66 infant cases.
- Review of bacterial culture results and antibiotic susceptibility tests.
- Comparison of complication rates with adult cases.
Main Results:
- Klebsiella pneumoniae was the predominant pathogen (48 cases).
- High susceptibility to imipenem, cefoperazone-sulbactam, and amikacin; resistance to ampicillin and nitrofurantoin.
- Lower anal fistula complication rate (6.6%) in infants compared to adults (60.3%).
Conclusions:
- Klebsiella pneumoniae is the most common pathogen in infant perianal abscesses.
- Optimal management includes simple surgical incision and sensitive antibiotic therapy.
- Perianal abscess in this age group is often self-limited, with favorable outcomes.
Abstract:
Zhu Y, Xu F. The pathogens and curative effects analysis of perianal abscess of infants under 3 months. Turk J Pediatr 2019; 61: 40-43. In order to guide clinical treatment for perianal abscess of young infants, the characteristics of pathogens and curative effects analysis were conducted. Bacterial culture results, antibiotics susceptibility tests and curative effects of abscess incision were retrospectively analyzed in 66 cases of perianal abscess of infants under 3 months. There were 48 cases of Klebsiella pneumoniae, 7 cases of Staphylococcus, 6 cases of Escherichia coli, 5 cases of Proteus in the pathogen culture results. Klebsiella pneumoniae, the predominant pathogen, was susceptible to most antibiotics, especially to imipenem, cefoperazonesulbactam and amikacin with low drug resistance rates. However, high drug resistance rates were found to ampicillin and nitrofurantion. After abscess incision, the complication rate of anal fistula was 6.6％ in infants under 3 months and 60.3％ in the adult group. There was significant difference P＜0.01. In conclusion, Klebsiella pneumoniae was the most common pathogen in perianal abscess of infants under 3 months and was commonly resistant to ampicillin and nitrofurantion. Since perianal abscess of infants under 3 months is a self-limited disorder, simple surgical intervention and synchronous sensitive antibiotic administration are suggested as the optimal management.
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