Pilomatrixomas in children: Report of 149 cases. A retrospective study at two children's hospitals

Area of Science:

• Dermatology
• Pediatric Oncology
• Surgical Pathology

Background:

• Pilomatrixoma is a benign skin neoplasm originating from hair follicle matrix cells, frequently observed in pediatric patients.
• Clinical presentation includes a firm, calcified nodule with characteristic skin changes.
• Diagnosis relies on clinical suspicion, imaging, and definitive histopathological examination.

Purpose of the Study:

• To analyze the epidemiological and clinical characteristics of pilomatrixomas in a pediatric cohort.
• To review diagnostic methods, including imaging and histology.
• To evaluate surgical techniques and outcomes for pilomatrixoma resection.

Main Methods:

• Retrospective review of 149 pilomatrixoma resections in 137 pediatric patients.
• Data collection included epidemiological, clinical, diagnostic, and surgical information.
• Analysis of cases treated at two specialized children's hospitals.

Main Results:

• Pilomatrixomas present as 0.5-3 cm nodules with calcified consistency and overlying skin changes.
• Diagnosis is typically suspected clinically and confirmed histologically.
• Surgical excision is the standard and effective treatment modality.

Conclusions:

• Pilomatrixoma is a common benign pediatric skin tumor with distinct clinical and histological features.
• Accurate diagnosis combines clinical assessment with histopathology.
• Surgical management provides a definitive treatment for pilomatrixoma.