Related Experiment Video
Updated: Jan 19, 2026

Experimental Multiscale Methodology for Predicting Material Fouling Resistance
Correlations between Fukui Indices and Reactivity Descriptors Based on Sanderson's Principle
1Departamento de Química-Física, Facultad de Ciencias, Campus Universitario Río San Pedro , Universidad de Cádiz , 11510 Puerto Real , Cádiz , Spain.
Abstract:
A previous study presented a very simple model mainly based on Sanderson's principle for estimating important reactivity descriptors, such as the local hardness and the local electrophilicity. In another study, a new way of calculating the Fukui function was obtained that resulted in a new operative formula for the function. We also obtained the second-order partial derivative of the electron density with regard to the number of electrons. The current study analyzes the relationships between the two models and justifies the origin of these relationships.
Related Concept Videos
Relative Reactivity of Carboxylic Acid Derivatives
A key factor in assessing the reactivity of the acid derivatives is the basicity of the substituent or the leaving group. The lower the basicity of the leaving group, the higher the reactivity of the derivative. The basicity of the leaving group follows this order:
Halide ions < Acyloxy ions < Alkoxy ions < Amine ions
Factors Affecting Activity Coefficient
The activity coefficient value for an ion is close to one when the solution has almost zero ionic strength, i.e., when the solution shows close to ideal behavior. As the ionic strength of the solution increases from 0 to 0.1 mol/L, a...
Atomic Radii and Effective Nuclear Charge
Factors Influencing the Rate of Chemical Reactions
Concentration and Pressure:
The more particles present within a given space, the more likely those particles are to bump into one another....
Arrhenius Plots
The Arrhenius equation can be used...
Ladder Diagrams: Redox Equilibria
Consider the Fe3+/Fe2+ half-reaction, which has a standard-state potential of +0.771 V. At potentials more positive than +0.771 V, Fe3+ predominates, whereas Fe2+...

