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Updated: Jan 19, 2026

Sample Preparation and Experimental Design for In Situ Multi-Beam Transmission Electron Microscopy Irradiation Experiments
Published on: June 27, 2022
Effects of Magnetic Field Applied Just Before, During or Immediately after Carbon-Ion Beam Irradiation on its
Taku Inaniwa1, Masao Suzuki2, Shinji Sato1
1Department of Accelerator and Medical Physics, National Institute of Radiological Sciences, QST, Chiba, Japan.
Abstract:
Previously reported studies have revealed that the application of a magnetic field longitudinal to a carbon-ion beam enhances its biological effectiveness. Here we investigated how timing of the magnetic field application with respect to beam irradiation influenced this effect. Human cancer cells were exposed to carbon-ion beams with linear energy transfer (LET) of 12 and 50 keV/µm. The longitudinal magnetic field of 0.3 T was applied to the cells just before, during or immediately after the beam irradiation. The effects of the timing on the biological effectiveness were evaluated by cell survival. The biological effectiveness increased only if the magnetic field was applied during beam irradiation for both LETs.
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