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The Price of Substitute Technologies.

André Soares Santos1, Augusto Afonso Guerra-Junior2, Kenya Valéria Micaela de Souza Noronha3

  • 1Department of Social Pharmacy, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; Núcleo de Avaliação de Tecnologias em Saúde do Hospital das Clínicas da Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; Department of Economical Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

Value in Health Regional Issues
|September 28, 2019
PubMed
Summary

The cost-effectiveness threshold (λ) for new drugs should be based on existing treatments to ensure fair pricing. This approach maximizes consumer benefit while encouraging pharmaceutical innovation and development.

Keywords:
cost-benefit analysiscost-effectiveness analysiscost-effectiveness thresholdshealth economicshealth technology assessment

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Area of Science:

  • Health economics
  • Pharmaceutical policy
  • Drug pricing regulation

Background:

  • Most new drugs offer minimal innovation over existing alternatives.
  • Health economic evaluations are crucial for setting acceptable prices for new health technologies.
  • Threshold pricing strategies can guide the regulation of new therapeutic agents.

Purpose of the Study:

  • To discuss a cost-effectiveness threshold (λ) for regulating the prices of substitute pharmaceutical technologies.
  • To establish a framework for fair pricing of new drugs based on their incremental value.

Main Methods:

  • Analysis of substitute technologies' marginal benefits and system efficiency.
  • Postulation of opportunity cost threshold (κ) as maximum value.
  • Identification of a threshold (β) that maximizes consumer surplus.
  • Formulation of a listing criterion: treatment cost of substitute technology must be less than incumbent's cost plus the threshold-priced effectiveness difference.

Main Results:

  • Pharmaceutical markets are unlikely to price drugs at production cost.
  • The cost-effectiveness ratio of incumbent technology, below κ, is a viable estimate for λ.
  • This estimate balances consumer benefit maximization with producer surplus for R&D incentives, falling between β and κ.

Conclusions:

  • Pricing of substitute technologies should be capped by the cost-effectiveness ratio of the incumbent technology.
  • This regulation ensures value-based pricing and supports continued innovation in the pharmaceutical sector.