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Elevated Plus Maze Test Combined with Video Tracking Software to Investigate the Anxiolytic Effect of Exogenous Ketogenic Supplements
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Ketogenic Diets and Exercise Performance.

Kristin L Harvey1, Lola E Holcomb2, Stephen C Kolwicz3

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The ketogenic diet (KD) and ketone supplements show promise for weight loss and exercise, but potential side effects warrant caution and further research into their metabolic effects.

Keywords:
endurance exerciseketone bodiesketone supplementsketosismetabolismobesity

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Area of Science:

  • Nutrition Science
  • Metabolic Health
  • Exercise Physiology

Background:

  • The ketogenic diet (KD) is popular for weight loss and energy production via ketone bodies.
  • Ketone body supplements are explored for exercise performance and ketosis induction.
  • Emerging research links KD and ketone metabolism to potential benefits for obesity, diabetes, and cardiac dysfunction.

Purpose of the Study:

  • To review ketone body metabolism, the KD, and ketone supplements.
  • To discuss their efficacy for weight loss and exercise performance.
  • To examine ketone metabolism's role in cardiac dysfunction.

Main Methods:

  • Literature review of scientific evidence on ketogenic diets and ketone body supplementation.
  • Analysis of studies investigating metabolic effects, including lipid profiles and glucose homeostasis.
  • Examination of research on ergogenic aid potential and cardiac applications.

Main Results:

  • The KD and ketone supplements show potential for obesity, diabetes, and exercise performance.
  • However, side effects like altered blood lipids, glucose issues, and fatigue are reported.
  • Ketone metabolism is increasingly recognized as a target for cardiac dysfunction treatment.

Conclusions:

  • The KD and ketone supplements offer potential therapeutic and performance benefits but require careful consideration of side effects.
  • Further research is needed to fully understand the long-term impacts and optimize applications.
  • Ketone body metabolism presents a promising avenue for addressing metabolic and cardiac conditions.