Tooth extraction in two patients who had a congenital deficiency of factor XIII

Two cases of the extraction of deciduous teeth in unrelated patients who had congenital Factor XIII deficiency are reported. The modes of inheritance of the deficiency are discussed, and methods of screening, diagnosis, and treatment are suggested. A combination of a local hemostatic treatment and transfusion of Factor XIII concentrate resulted in the sockets healing without further postoperative bleeding in both cases.