Correlations Between Different Choriocapillaris Flow Deficit Parameters in Normal Eyes Using Swept Source OCT...

Area of Science:

• Ophthalmology
• Medical Imaging
• Retinal Vascular Diseases

Background:

• Choriocapillaris (CC) imaging is crucial for understanding retinal health.
• Swept-source optical coherence tomographic angiography (SS-OCTA) provides detailed visualization of CC.
• Quantifying CC abnormalities is essential for diagnosing and monitoring eye conditions.

Purpose of the Study:

• To compare choriocapillaris flow deficits percentage (FD%) and average area (FDa) in normal eyes.
• To evaluate the correlation between FD% and FDa across different macular regions using SS-OCTA.
• To determine the reliability of these metrics for future research.

Main Methods:

• Prospective, cross-sectional study involving 164 normal eyes.
• SS-OCTA imaging with 3x3-mm and 6x6-mm macular scan patterns.
• Measurement of CC FD% and FDa in circular regions (1mm, 2.5mm, 5mm diameters) and analysis using Pearson correlation coefficients.

Main Results:

• Excellent correlation was observed between CC FDa and FD% measurements across all analyzed regions.
• In 3x3-mm scans, correlations were 0.83 (C1) and 0.90 (C2.5).
• In 6x6-mm scans, correlations were 0.90 (C1), 0.89 (C2.5), and 0.89 (C5).

Conclusions:

• High correlation between FDa and FD% in CC measurements using SS-OCTA in normal eyes.
• Both metrics are reliable for quantifying CC flow deficits.
• Further research is needed to ascertain the utility of each parameter in diseased eyes.