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The nuts and bolts of omics for the clinical allergist
Yamini V Virkud1, Rachel S Kelly2, Caleb Wood2
1Department of Pediatrics, Massachusetts General Hospital for Children and Harvard Medical School, Boston, Massachusetts; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Objective:
Omics, aka multi-omics, is an emerging area of research that is advancing the use of personalized medicine in clinical practice and is therefore relevant for the practicing allergist.
Data Sources:
We performed a literature search of a selection of scientific findings in omics and allergy, including variants that may be important to allergy outcomes in the genome, transcriptome, metabolome, microbiome, epigenome, and exposome, among others.
Study Selections:
Basic science papers and review articles.
Results:
The use of multi-omic data in clinical practice is changing how clinicians treat their patients whereby more personalized approaches are becoming standard in medical practice and has the potential to transform the treatment of allergies.
Conclusion:
Multi-omic data are relevant and will become increasingly important for the clinical allergist.
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