Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Antiepileptic Drugs: Glutamate Antagonists01:14

Antiepileptic Drugs: Glutamate Antagonists

906
Glutamate is a fundamental neurotransmitter in the central nervous system, playing a vital role in neuronal communication and various cognitive processes. Glutamate stands as the principal excitatory neurotransmitter in the brain. Its presence is crucial for the communication between neurons, underpinning essential processes such as synaptic transmission, neuronal excitability, and plasticity. These functions are vital for higher-order cognitive processes, including learning and memory. The...
906
Mania and Antimanic Drugs: Overview01:24

Mania and Antimanic Drugs: Overview

561
Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as...
561
Cholinergic Antagonists: Therapeutic Uses01:26

Cholinergic Antagonists: Therapeutic Uses

1.4K
Antimuscarinic drugs have various therapeutic applications by inhibiting parasympathetic stimulation in different systems. Here are the key therapeutic uses of antimuscarinics:    
Respiratory Tract: Ipratropium, aclidinium, and tiotropium treat asthma, chronic bronchitis, and chronic obstructive pulmonary disease (COPD). They protect against bronchoconstriction caused by irritants like cigarette smoke, sulfur dioxide, and ozone. They also help reduce nasopharyngeal...
1.4K
Preventive Healthcare Services01:30

Preventive Healthcare Services

1.9K
Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
1.9K
Chemotherapy-Induced Nausea and Vomiting: 5-HT3 Receptor Antagonists01:27

Chemotherapy-Induced Nausea and Vomiting: 5-HT3 Receptor Antagonists

606
5-HT3 receptor antagonists, such as dolasetron, granisetron (Kytril), ondansetron (Zofran), and palonosetron (Axoli), are crucial in managing chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea. These drugs selectively block 5-HT3 receptors in the visceral vagal and spinal afferent nerves, chemoreceptor trigger zone, and the vomiting center. They have a rapid onset of action and can be given as a single dose before chemotherapy. Ondansetron and granisetron, in particular,...
606
Parkinson's Disease: Treatment01:24

Parkinson's Disease: Treatment

995
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
995

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spinal CSF-Venous Fistulas as the Potential Cause of Chronic Subarachnoid Hemorrhage: Superficial Siderosis and Adhesive Arachnoiditis.

AJNR. American journal of neuroradiology·2026
Same author

The Interictal State of Migraine: Understanding the Hidden Burden Between Attacks.

Current pain and headache reports·2026
Same author

Consensus Guidelines on Diagnostic Brain and Spine Imaging of Spontaneous Intracranial Hypotension.

AJNR. American journal of neuroradiology·2025
Same author

International Headache society evidence-based guidelines on the use of non-invasive neuromodulation devices for the acute and preventive treatment of migraine.

Cephalalgia : an international journal of headache·2025
Same author

The contribution of lumbar puncture opening pressure in the diagnosis of spontaneous intracranial hypotension: A systematic literature review and meta-analysis.

Headache·2025
Same author

Practice advisory for intravenous management of headache disorders in hospitalized patients: a review of the evidence and consensus recommendations.

Regional anesthesia and pain medicine·2025

Related Experiment Video

Updated: Jan 18, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

18.7K

Preventive Treatment for Episodic Migraine.

Simy K Parikh1, Stephen D Silberstein1

  • 1Jefferson Headache Center, Thomas Jefferson University Hospital, Thomas Jefferson University, 900 Walnut Street, Suite #200, Philadelphia, PA 19107, USA.

Neurologic Clinics
|September 30, 2019
PubMed
Summary

This review covers new and established preventive treatments for episodic migraine, including CGRP monoclonal antibodies and updated guideline recommendations. It focuses on reducing migraine attack frequency, duration, and severity.

Keywords:
CGRP monoclonal antibodiesDiagnosisEpisodic migraineHeadachePreventionSingle-pulse transcranial magnetic stimulatorTranscutaneous electrical nerve stimulationTreatment

More Related Videos

Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders
05:49

Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders

Published on: November 1, 2024

1.2K
Investigating Migraine-Like Behavior Using Light Aversion in Mice
05:23

Investigating Migraine-Like Behavior Using Light Aversion in Mice

Published on: August 11, 2021

4.4K

Related Experiment Videos

Last Updated: Jan 18, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

18.7K
Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders
05:49

Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders

Published on: November 1, 2024

1.2K
Investigating Migraine-Like Behavior Using Light Aversion in Mice
05:23

Investigating Migraine-Like Behavior Using Light Aversion in Mice

Published on: August 11, 2021

4.4K

Area of Science:

  • Neurology
  • Headache Medicine

Background:

  • Episodic migraine significantly impacts quality of life.
  • Preventive therapy aims to decrease migraine attack frequency, duration, and severity.

Purpose of the Study:

  • To review current principles of preventive treatment for episodic migraine.
  • To discuss evidence-based updates on new and established therapeutic options.

Main Methods:

  • Literature review of preventive treatments for episodic migraine.
  • Analysis of new migraine-specific therapies: CGRP monoclonal antibodies, noninvasive electrical nerve stimulation, and transcranial magnetic stimulation.
  • Inclusion of updated guideline recommendations from the American Academy of Neurology and American Headache Society.

Main Results:

  • New migraine-specific treatments, including CGRP monoclonal antibodies, show promise.
  • Noninvasive neuromodulation devices offer alternative preventive strategies.
  • Updated guidelines provide evidence-based recommendations for major medication classes.

Conclusions:

  • A range of effective preventive options exist for episodic migraine.
  • Treatment selection should consider individual patient needs and evidence-based guidelines.
  • Ongoing research continues to expand therapeutic possibilities for migraine prevention.