Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Estimation of the Physical Quantities01:05

Estimation of the Physical Quantities

7.2K
On many occasions, physicists, other scientists, and engineers need to make estimates of a particular quantity. These are sometimes referred to as guesstimates, order-of-magnitude approximations, back-of-the-envelope calculations, or Fermi calculations. The physicist Enrico Fermi was famous for his ability to estimate various kinds of data with surprising precision. Estimating does not mean guessing a number or a formula at random. Instead, estimation means using prior experience and sound...
7.2K
Statistical Analysis: Overview01:11

Statistical Analysis: Overview

15.0K
When we take repeated measurements on the same or replicated samples, we will observe inconsistencies in the magnitude. These inconsistencies are called errors. To categorize and characterize these results and their errors, the researcher can use statistical analysis to determine the quality of the measurements and/or suitability of the methods.
One of the most commonly used statistical quantifiers is the mean, which is the ratio between the sum of the numerical values of all results and the...
15.0K
Uncertainty in Measurement: Reading Instruments02:46

Uncertainty in Measurement: Reading Instruments

50.3K
Counting is the type of measurement that is free from uncertainty, provided the number of objects being counted does not change during the process. Such measurements result in exact numbers. By counting the eggs in a carton, for instance, one can determine exactly how many eggs are there in the carton. Similarly, the numbers of defined quantities are also exact. For example, 1 foot is exactly 12 inches, 1 inch is exactly 2.54 centimeters, and 1 gram is exactly 0.001 kilograms. Quantities...
50.3K
Quantitative Analysis01:12

Quantitative Analysis

1.3K
Quantitative analysis is a technique for measuring the amount of specific constituents in a sample. When the sample's composition is unknown, qualitative analysis is performed first to identify its components, which ensures that the correct substances are measured during the quantitative phase.
In quantitative analysis, two key measurements are made: the sample quantity and a property proportional to the amount of the analyte (the substance being analyzed). This forms the basis of the...
1.3K
Accuracy and Precision01:52

Accuracy and Precision

14.1K
Scientists typically make repeated measurements of a quantity to ensure the quality of their findings and to evaluate both the precision and the accuracy of their results. Measurements are said to be precise if they yield very similar results when repeated in the same manner. A measurement is considered accurate if it yields a result that is very close to the true or the accepted value. Precise values agree with each other; accurate values agree with a true value.  Highly accurate...
14.1K
Uncertainty in Measurement: Accuracy and Precision03:37

Uncertainty in Measurement: Accuracy and Precision

99.9K
Scientists typically make repeated measurements of a quantity to ensure the quality of their findings and to evaluate both the precision and the accuracy of their results. Measurements are said to be precise if they yield very similar results when repeated in the same manner. A measurement is considered accurate if it yields a result that is very close to the true or the accepted value. Precise values agree with each other; accurate values agree with a true value. 
99.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tree-based exploratory identification of predictive biomarkers in non-randomized data.

BMC medical research methodology·2026
Same author

Clustered monoallelic mosaicism in twins suggests previously unrecognized path of mutagenesis.

HGG advances·2026
Same author

Correction: Paediatric Phase I/II Clinical Trial Assessments Under the New EU Clinical Trial Regulation: A Descriptive Analysis.

Pharmaceutical medicine·2026
Same author

Interpreting [<sup>18</sup>F]FDG-avid fractures after induction therapy in multiple myeloma: insights from the PET/CT sub-study of the Phase 3 GMMG-HD7 trial.

European journal of nuclear medicine and molecular imaging·2026
Same author

Beyond target lesions: Prognostic value of longitudinal AI-derived whole-body [<sup>1</sup>⁸F]FDG PET/CT metrics in metastatic melanoma.

European journal of nuclear medicine and molecular imaging·2026
Same author

Incorporating functional soft tissue deformations in AI model training for spatially accurate prostate cancer detection.

Magnetic resonance imaging·2026
Same journal

Definitive IMRT alone with reduced prophylactic nodal irradiation for Early-Stage Oropharyngeal Cancer: JCOG1208.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026
Same journal

Associations between body composition and radiotherapy-related side-effects and health-related quality of life in patients with prostate or lung cancer: sub-analysis of the REQUITE trial.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026
Same journal

ESTRO recommendations for the use, planning and delivery of reirradiation in locally recurrent rectal cancer - Endorsed by ASTRO.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026
Same journal

Early ADC changes in risk-model-defined brain regions precede contrast-enhancing lesions after proton therapy for low-grade glioma.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026
Same journal

Any impact of pre-operative radiotherapy on renal function in retroperitoneal soft tissue sarcomas? A secondary ancillary analysis of the EORTC 62092 STRASS 1 trial.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026
Same journal

Tumor volume reduction during adaptive radiotherapy is a strong prognostic factor for oropharyngeal cancer: A retrospective multicenter study?

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026
See all related articles

Related Experiment Video

Updated: Jan 18, 2026

Software-Assisted Quantitative Measurement of Osteoarthritic Subchondral Bone Thickness
08:52

Software-Assisted Quantitative Measurement of Osteoarthritic Subchondral Bone Thickness

Published on: March 18, 2022

3.4K

How to evaluate agreement between quantitative measurements.

Annette Kopp-Schneider1, Thomas Hielscher1

  • 1Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany.

Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
|September 30, 2019
PubMed
Summary
This summary is machine-generated.

The Bland-Altman plot is the correct method for analyzing measurement agreement in comparative studies. This analysis provides limits of agreement, unlike other inappropriate indices.

Keywords:
AgreementBland–Altman plotConcordance Correlation CoefficientLimits of agreementMethod comparison study

More Related Videos

Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes
05:58

Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes

Published on: March 22, 2022

4.5K
Author Spotlight: Assessing the Reliability of Doppler Ultrasound in Measuring Leg Blood Flow
09:18

Author Spotlight: Assessing the Reliability of Doppler Ultrasound in Measuring Leg Blood Flow

Published on: December 15, 2023

3.4K

Related Experiment Videos

Last Updated: Jan 18, 2026

Software-Assisted Quantitative Measurement of Osteoarthritic Subchondral Bone Thickness
08:52

Software-Assisted Quantitative Measurement of Osteoarthritic Subchondral Bone Thickness

Published on: March 18, 2022

3.4K
Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes
05:58

Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes

Published on: March 22, 2022

4.5K
Author Spotlight: Assessing the Reliability of Doppler Ultrasound in Measuring Leg Blood Flow
09:18

Author Spotlight: Assessing the Reliability of Doppler Ultrasound in Measuring Leg Blood Flow

Published on: December 15, 2023

3.4K

Area of Science:

  • Biostatistics
  • Medical Research Methodology
  • Data Analysis

Background:

  • Method comparison studies are crucial for evaluating the reliability of different measurement techniques.
  • Assessing agreement between methods is essential for clinical decision-making and quality control.
  • Existing agreement indices are often misused or misinterpreted.

Purpose of the Study:

  • To present the Bland-Altman plot and limits of agreement as the definitive methodology for assessing measurement agreement.
  • To critically evaluate various scaled and unscaled agreement indices.
  • To highlight and discourage the use of inappropriate analysis approaches in method comparison studies.

Main Methods:

  • Detailed explanation and application of the Bland-Altman plot.
  • Comparative analysis of different agreement metrics.
  • Discussion of statistical principles underlying agreement assessment.

Main Results:

  • The Bland-Altman plot with limits of agreement is demonstrated as the most appropriate method.
  • Commonly used agreement indices are shown to be insufficient or misleading.
  • Misapplication of statistical methods in agreement studies is identified.

Conclusions:

  • The Bland-Altman plot is the gold standard for method comparison studies.
  • Researchers should adopt the Bland-Altman method for accurate agreement assessment.
  • Awareness of inappropriate methods is critical to avoid erroneous conclusions in scientific research.