The relationship of volume overload and its control to hypertension in hemodialysis patients
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Published on: October 2, 2020
Jennifer E Flythe1,2, Nisha Bansal3,4
1Division of Nephrology and Hypertension, Department of Medicine, University of North Carolina Kidney Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina.
Insights
Hypertension and volume overload are common in hemodialysis patients, worsening outcomes. Addressing these challenges is crucial for improving patient health and care experiences.
Area of Science:
- Nephrology
- Cardiovascular Medicine
Background:
- Hypertension is prevalent in hemodialysis (HD) patients, linked to adverse clinical outcomes.
- Volume overload is a significant modifiable factor contributing to hypertension and cardiovascular disease in this population.
- Managing volume overload and hypertension in HD patients presents considerable clinical challenges.
Purpose of the Study:
- To review current data on hypertension and volume overload in HD patients.
- To cover diagnosis, epidemiology, pathophysiology, and clinical consequences.
- To identify future research priorities in this area.
Main Methods:
- Literature review of existing data.
- Synthesis of information on diagnosis and management.
- Identification of knowledge gaps and research needs.
Main Results:
- Hypertension and volume overload significantly impact HD patient outcomes.
- Current assessment and treatment strategies face challenges.
- Further research is needed to optimize care.
Conclusions:
- Effective management of hypertension and volume overload is critical for HD patients.
- Addressing these issues can improve clinical outcomes and patient experiences.
- Future research should focus on enhancing diagnostic and therapeutic approaches.
Abstract:
Hypertension is highly prevalent and associated with poor clinical outcomes among individuals receiving maintenance hemodialysis (HD). Volume overload is a key modifiable contributor to hypertension and cardiovascular disease in the HD population. Despite their importance, assessment and treatment of volume overload and hypertension remain major clinical challenges and have substantial implications for both clinical outcomes and patient experiences of care. This review will summarize current data on the diagnosis, epidemiology, pathophysiology, and clinical consequences of hypertension and volume overload in HD patients. We will also identify priorities for future research studies.
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