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Retrovirus Life Cycles

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Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...

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Related Experiment Video

Updated: Jan 18, 2026

Lentivirus Production

Lentivirus Production

Published on: October 2, 2009

Editorial overview: Lassa virus

Connie Schmaljohn¹, David Safronetz²

¹U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702, United States.

Current Opinion in Virology

|October 1, 2019

Summary

No abstract available in PubMed .

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