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Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
Published on: October 28, 2020
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Right Ventricular Diastolic Function and Right Atrial Function and Their Relation With Exercise Capacity in Ebstein
Yohei Akazawa1, Tao Fujioka1, Andreas Kühn2
1Division of Cardiology, The Labatt Family Heart Centre, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
The Canadian Journal of Cardiology
|October 1, 2019
Summary
Right atrial (RA) and right ventricular (RV) diastolic dysfunction in Ebstein anomaly (EA) are linked to reduced exercise capacity. Evaluating RA function is crucial for managing EA patients.
Area of Science:
- Cardiology
- Cardiac Imaging
- Exercise Physiology
Background:
- Right ventricular (RV) and right atrial (RA) diastolic function are not well understood in Ebstein anomaly (EA).
- These functions may significantly impact the functional capacity of EA patients.
- Previous research has not fully explored the relationship between RV/RA function and exercise capacity in EA.
Purpose of the Study:
- To assess RV diastolic and RA function in patients with EA.
- To investigate the association between RV/RA function and biventricular systolic function.
- To determine the relationship between RV/RA function and exercise capacity in EA.
Main Methods:
- Prospective study involving 72 EA patients and 69 controls.
- Utilized echocardiography, cardiovascular magnetic resonance imaging, and cardiopulmonary exercise testing.
- Evaluated RV systolic and diastolic function, RA function, and exercise capacity (peak VO2).
Main Results:
- EA patients exhibited impaired RV diastolic function, evidenced by altered tricuspid valve E/A ratio, filling time, strain rates, and myocardial performance index.
- Impaired RA reservoir, conduit, and pump function were observed in EA patients.
- RV diastolic function and RA function correlated with biventricular systolic function and exercise capacity (peak VO2). RA reservoir function showed a strong association with peak VO2 (r=0.54).
Conclusions:
- Altered RV diastolic and RA function are associated with impaired biventricular systolic function and exercise capacity in EA.
- RA function appears to have a stronger correlation with exercise capacity than RV function in EA.
- Comprehensive evaluation of RA function is recommended for managing patients with Ebstein anomaly.
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