Related Experiment Video
Updated: Jan 18, 2026

13:35
Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
4.1K
Primary Angiosarcoma Of the Breast: A Case Report
Beenu Varghese1, Pooja Deshpande1, Santosh Dixit1
1Orchids Breast Health Centre, Prashanti Cancer Care Mission, Pune, Maharashtra, India.
Journal of Radiology Case Reports
|October 1, 2019
Summary
Primary breast angiosarcoma is rare and challenging to diagnose due to non-specific features. Early recognition by radiologists is crucial for this aggressive malignancy, often misdiagnosed initially.
Area of Science:
- Oncology
- Radiology
- Pathology
Background:
- Primary breast angiosarcoma is a rare malignancy, accounting for 0.04% of all malignant breast tumors.
- It predominantly affects younger patients and presents with variable clinical, radiological, and pathological features, complicating diagnosis.
- The non-specific presentation often leads to misdiagnosis by both radiologists and pathologists.
Observation:
- A 32-year-old female presented with non-specific imaging findings suggestive of a breast lesion.
- An initial ultrasound-guided biopsy was misinterpreted as a capillary cavernous hemangioma on histopathology.
Findings:
- Radiology-pathology discordance prompted a second histopathological opinion.
- The second opinion definitively diagnosed the lesion as primary breast angiosarcoma.
Implications:
- Radiologists must maintain a high index of suspicion for angiosarcoma, even with non-specific imaging findings.
- Awareness of potential misdiagnosis is critical for accurate and timely diagnosis of this rare breast cancer.
- Prompt diagnosis and appropriate management are essential for improving patient outcomes in primary breast angiosarcoma.

