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Updated: Jan 18, 2026

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
Published on: February 28, 2012
Acute Device-Related Thrombus after Watchman Device Implant
Muhammad Ajmal1,2, Vijendra Swarup1,3
1St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.
Insights
Atrial fibrillation increases stroke risk. Left atrial appendage closure with the Watchman device can prevent clots, but may cause device-related thrombus, requiring management strategies.
Area of Science:
- Cardiology
- Medical Devices
- Thrombosis Management
Background:
- Atrial fibrillation (AF) presents an irregular heart rhythm, elevating risks of stroke and mortality due to potential blood clot formation, primarily in the left atrial appendage (LAA).
- Anticoagulant therapy is standard for reducing thromboembolism risk in AF patients.
- Percutaneous LAA closure using devices like the Watchman offers an alternative for patients with high bleeding risks who cannot tolerate anticoagulants.
Observation:
- The Watchman device, used for LAA closure, is associated with potential adverse events, including device-related thrombus (DRT).
- Acute DRT can form rapidly after Watchman device implantation.
- Current clinical guidelines for managing acute DRT following LAA closure are lacking.
Findings:
- This case report details an instance of Watchman device-related thrombus occurring just 16 hours post-implantation.
- The study highlights the rapid onset of DRT after LAA closure procedures.
Implications:
- The findings underscore the need for prompt recognition and management of acute DRT after Watchman device placement.
- Further research is warranted to establish specific clinical guidelines for the management of DRT to optimize patient outcomes.
- This case contributes to the understanding of early complications associated with LAA closure devices.
Abstract:
Atrial fibrillation is characterized by irregularly irregular heart rhythm with an increased morbidity and mortality. It is associated with an increased risk of thromboembolism due to formation of blood clot in the left atrium. Most of these blood clots are formed in the left atrial appendage. The risk of blood clot formation is reduced with the use of anticoagulants. The patients who cannot take anticoagulants due to an increased bleeding risk can undergo percutaneous left atrial appendage (LAA) closure. A Watchman device is used for this purpose. LAA closure with the Watchman device is associated with some adverse effects, and one of them is device-related thrombus. Currently, there are no specific guidelines for the management of device-related thrombus. We present a case of Watchman device-related thrombus which developed 16 hours after the device placement. We will also discuss various options for the management of acute thrombosis.
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