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Vomiting in Neuromyelitis Optica: An Atypical Presentation
Syed M Zaidi1, Aleena Mohib2, Syed Asad Hasan Rizvi3
1Internal Medicine, Civil Hospital Karachi, Dow University of Health Sciences, Karachi, PAK.
Cureus
|October 1, 2019
Summary
Neuromyelitis Optica Spectrum Disorder (NMOSD) can present with unusual symptoms like intractable vomiting. Early diagnosis of this autoimmune CNS disorder is crucial for preventing severe disability.
Area of Science:
- Neuroimmunology
- Neurology
- Autoimmune Disorders
Background:
- Neuromyelitis Optica (NMO), or Devic's disease, is a central nervous system demyelinating autoimmune disorder.
- NMO primarily affects the optic nerves and spinal cord, leading to visual and motor deficits.
Observation:
- A case study of an 18-year-old female presenting with intractable vomiting and epigastric pain, initially misdiagnosed.
- The patient later developed double vision and inability to stand or walk, prompting further investigation.
Findings:
- Diagnosis confirmed as Neuromyelitis Optica Spectrum Disorder (NMOSD) based on the presence of anti-NMO antibodies.
- Intractable vomiting was identified as an atypical but significant presenting symptom.
Implications:
- Highlights the importance of considering NMOSD in patients with unexplained severe vomiting.
- Prompt diagnosis and treatment of NMOSD are essential to prevent irreversible neurological damage and disability.
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