Related Experiment Video

Updated: Jan 18, 2026

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
04:50

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain

Published on: May 16, 2025

830

Spontaneous Coronary Artery Dissection Secondary to Rheumatological Diseases: A Comprehensive Review

Waqas Ullah1, Zain Ali1, Shristi Khanal1

  • 1Internal Medicine, Abington Hospital-Jefferson Health, Abington, USA.

Cureus
|October 1, 2019
PubMed

Insights

Spontaneous coronary artery dissection (SCAD) is linked to rheumatological diseases, particularly systemic lupus erythematosus (SLE). Early diagnosis and treatment of SCAD in these patients are crucial for survival.

Area of Science:

  • Cardiology
  • Rheumatology
  • Medical Research

Background:

  • Spontaneous coronary artery dissection (SCAD) is a critical cardiovascular condition.
  • Several underlying conditions are associated with SCAD.
  • The link between rheumatological diseases and SCAD requires further investigation.

Purpose of the Study:

  • To investigate and characterize the association between rheumatological diseases and SCAD.
  • To identify specific rheumatological conditions linked to SCAD.
  • To analyze the clinical presentation and management of SCAD in patients with rheumatological conditions.

Main Methods:

  • A comprehensive literature search was conducted across four databases.
  • Articles focusing on SCAD associated with rheumatological diseases were identified using Medical Subject Headings (MeSH).
  • Data analysis was performed using SPSS v22.

Main Results:

  • Ten articles detailing SCAD secondary to rheumatological conditions were identified.
  • Systemic lupus erythematosus (SLE) was the most frequently associated rheumatological disease.
  • Most patients presented with non-ST-elevation myocardial infarction (NSTEMI) affecting the left main coronary artery.
  • Stenting was the primary successful management strategy.
  • Mortality was under 20% with prompt diagnosis and management.

Conclusions:

  • Systemic lupus erythematosus (SLE) is the most common rheumatological condition associated with SCAD.
  • Prompt diagnosis and effective management of SCAD in patients with rheumatological diseases are vital for improving outcomes and saving lives.

Keywords:
coronary stentingspontaneous coronary artery dissectionsystemic lupus erythematosus

More Related Videos

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice07:37

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice

Published on: June 6, 2025

1.0K
Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

20.8K

Related Concept Videos

Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
448
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
501
Rheumatic Heart Disease III: Medical Management01:21

Rheumatic Heart Disease III: Medical Management

Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
290
Rheumatic Heart Disease IV: Nursing Management01:20

Rheumatic Heart Disease IV: Nursing Management

AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...
276
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
15.3K
Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
472